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- NOTE: Teams listed in alphabetical order
INJURIES
- RB Bam Knight (ankle) was a limited practice participant.
- WR Simi Fehoko was placed on injured reserve.
- WR Marvin Harrison Jr. will miss Sunday's game against the 49ers after undergoing an appendectomy, per head coach Jonathan Gannon.
- WR Zay Jones was placed on IR.
- DL Darius Robinson (groin) limited
- DT Bilal Nichols (personal) DNP
- DL Walter Nolen (knee) limited
- LB Baron Browning (concussion)
- LB BJ Ojulari (knee) limited
- CB Will Johnson (back/hip) did not practice.
SIGNINGS
- WR Andre Baccellia (from practice squad)
- WR Jalen Virgil (practice squad)
- CB Jaden Davis (practice squad)
3-6
INJURIES
- WR Drake London (illness) did not practice Wednesday.
- G Matthew Bergeron is considered day to day, head coach Raheem Morris said. Bergeron did not practice.
- G Chris Lindstrom (foot) DNP
- OL Storm Norton reverted to injured reserve and is out for the remainder of the season.
- DL LaCale London (shoulder) was a full participant in practice.
- LB Leonard Floyd (hamstring) DNP
- LB DeAngelo Malone (ankle) will go on IR, Morris said.
- LB Malik Verdon was designated to return from the non-football injury list and was limited in practice.
- LB Josh Woods (hamstring) DNP
- CB Dee Alford (concussion) limited
- CB Mike Hughes (neck) limited
SIGNINGS
- S Jammie Robinson (practice squad)
4-5
INJURIES
- QB Lamar Jackson did not practice Wednesday due to knee soreness but should be OK and back at practice Thursday, head coach John Harbaugh said.
- RB Justice Hill (toe) DNP
- RB Keaton Mitchell (knee) was limited in practice.
- WR Rashod Bateman (ankle) DNP
- TE Isaiah Likely (hip) limited
- CB Marlon Humphrey (finger) will not play Sunday against the Browns but ill hopefully be back in the next week, Harbaugh said.
- S Malaki Starks (knee) limited
6-3
SIGNINGS
- DE Morgan Fox (practice squad)
ROSTER CUTS
- P Cam Johnston was released from injured reserve.
INJURIES
- WR Josh Palmer (knee/ankle) was a full participant in Wednesday's practice.
- WR Khalil Shakir (ribs) was limited in practice.
- TE Dalton Kincaid (hamstring) did not practice.
- DT Phidarian Mathis (shoulder) DNP
- DT Jordan Phillips (knee/ankle) full
- DE Joey Bosa (wrist) limited
- DE A.J. Epenesa (concussion) full
- DE Landon Jackson (knee) is being placed on injured reserve, McDermott said.
- LB Terrel Bernard (ankle) limited
- LB Shaq Thompson (hamstring) limited
- CB Christian Benford (groin) limited
- CB Taron Johnson (groin) limited
INJURIES
- RB Rico Dowdle (quad) did not practice Wednesday. Dowdle is expected to practice Thursday, head coach Dave Canales said.
- G Chandler Zavala (elbow) was a full participant in practice.
- DT Derrick Brown (knee) was limited in practice. Canales said Brown's knee issue is not serious and he is expected to practice Thursday.
- LB Trevin Wallace (shoulder) is considered week to week, Canales said. Wallace didn't practice Wednesday.
- S Lathan Ransom (hand) DNP
6-3
INJURIES
- RB D'Andre Swift (hip) was limited in Wednesday's practice.
- WR DJ Moore (shoulder) did not practice.
- WR Rome Odunze (ankle) DNP
- TE Cole Kmet (back) limited
- LB T.J. Edwards (hand/hamstring) DNP
- LB Ruben Hyppolite II (knee) was a full participant in practice.
- DB Jaquan Brisker (back) DNP
- DB Tyrique Stevenson (shoulder) DNP
INJURIES
- QB Joe Burrow (toe) was limited in Wednesday's practice.
- QB Joe Flacco (right shoulder) did not practice.
- RB Samaje Perine (ankle) DNP
- DE Trey Hendrickson (hip) remains doubtful for Sunday's game against the Steelers, head coach Zac Taylor said. Henderson did not practice Wednesday.
- DE Shemar Stewart (knee) is week to week, Taylor said. Stewart did not practice Wednesday.
- CB Marco Wilson (hamstring) was a full practice participant.
2-7
SIGNINGS
- WR Kaden Davis (from practice squad)
ROSTER CUTS
- DB Tre Avery
INJURIES
- WR Isaiah Bond (foot) was limited in Wednesday's practice.
- WR Cedric Tillman (glute) limited
- TE Harold Fannin Jr. (hamstring) limited
- OT Cornelius Lucas (back) limited
- DE Alex Wright (quad) did not practice.
- LB Jerome Baker (Achilles) limited
- LB Carson Schwesinger (shoulder) limited
3-5-1
8-2
SIGNINGS
- DE Garrett Nelson (practice squad)
ROSTER CUTS
INJURIES
- RB J.K. Dobbins (foot) did not practice Wednesday.
- WR Marvin Mims Jr. (concussion) was a full participant.
- WR Trent Sherfield (toe) DNP
- TE Nate Adkins (knee) DNP
- OLB Jonathon Cooper (thumb) full
- ILB Alex Singleton (illness) DNP
- LB Garret Wallow (hamstring) was designated to return from injured reserve and a full participant.
- CB Patrick Surtain II (pectoral) DNP
6-3
INJURIES
- TE Sam LaPorta (back) did not practice Wednesday.
- OT Taylor Decker (shoulder) was limited in practice.
- OT Penei Sewell (ankle) DNP
- C Graham Glasgow (back) limited
- DE Marcus Davenport's 21-day practice window was opened and he participated Wednesday in a limited capacity.
- DE Aidan Hutchinson (elbow) DNP
- DE Joshua Paschal (back) limited
- LB Malcolm Rodriguez (knee) was a full participant in practice.
- CB Terrion Arnold (concussion) DNP
- CB D.J. Reed's 21-day practice window was opened and he participated in a limited capacity.
- S Kerby Joseph (knee) DNP
5-3-1
INJURIES
- WR Romeo Doubs, who left Monday's loss to the Eagles with a chest injury, should be good to go for Sunday's game against the Giants, head coach Matt LaFleur said. Doubs was estimated as a full participant in Wednesday's walkthrough practice.
- WR Matthew Golden (shoulder) was estimated as a limited practice participant.
- WR Dontayvion Wicks (calf) limited
- WR Savion Williams (foot) limited
- OL Elgton Jenkins, who was placed on injured reserve Tuesday with a broken bone in his leg, is highly unlikely to return this season, LaFleur said.
- DL Kingsley Enagbare (knee) limited
- DL Micah Parsons (pectoral) limited
- LB Edgerrin Cooper (foot) limited
- LB Lukas Van Ness (foot) did not practice.
- LB Quay Walker (calf) limited
- CB Nate Hobbs (knee) DNP
SIGNINGS
- OL Lecitus Smith (practice squad)
4-5
INJURIES
- QB Davis Mills (left elbow) was a full participant in Wednesday's practice.
- QB C.J. Stroud (concussion) did not practice.
- FB Jakob Johnson (hamstring) was a full participant in practice.
- TE Harrison Bryant (neck/shoulder) DNP
- TE Dalton Schultz (shoulder) DNP
- TE Cade Stover had his 21-day window opened and returned to practice as a limited participant.
- G Ed Ingram (knee) limited
- OL Tytus Howard (concussion) full
- DE Denico Autry (knee) DNP
- LB Azeez Al-Shaair (knee) limited
- LB Jake Hansen (elbow) limited
- LB Christian Harris (shin) full
- S Jalen Pitre (concussion) DNP
- S M.J. Stewart was placed on injured reserve.
- K Ka'imi Fairbairn (right quad) DNP
SIGNINGS
- TE Layne Pryor (practice squad)
- CB Myles Bryant (from practice squad)
TRYOUTS
INJURIES
- WR Parker Washington (hamstring) did not practice.
- WR Brian Thomas Jr. (ankle) was a limited practice participant.
- TE Hunter Long (hip/knee) DNP
- TE Brenton Strange's 21-day practice window to return from injured reserve was opened. Strange (hip/quad) was placed on injured reserve on Oct. 7.
- LB Dennis Gardeck (chest) limited
- CB Jourdan Lewis (neck) DNP
- CB Greg Newsome II (shoulder) limited
SIGNINGS
- WR Jimmy Holiday (practice squad)
INJURIES
- RB Isiah Pacheco (knee) did not practice Wednesday.
- G Trey Smith (back) was a full participant in practice.
- OT Josh Simmons (personal) full
- OT Jawaan Taylor (knee/ankle) full
- DE George Karlaftis (thumb) was limited in practice.
- DE Charles Omenihu (ankle) full
- S Jaden Hicks (pectoral) full
SIGNINGS
- WR Luke Grimm (practice squad)
INJURIES
- WR Quentin Johnston (shin) was limited at practice.
- WR Ladd McConkey (ankle) limited
- TE Oronde Gadsden II (knee) full
- OT Bobby Hart (knee) limited
- LB Daiyan Henley (ankle) limited
- CB Tarheeb Still (knee) limited
7-2
INJURIES
- WR Davante Adams (oblique) did not practice Wednesday but is expected to play Sunday against the Seahawks, head coach Sean McVay said.
- WR Jordan Whittington (back) limited
- DE Kobie Turner (back) DNP
- CB Darious Williams (shoulder) full
3-7
INJURIES
- RB Ollie Gordon II (ankle) was limited in Wednesday's practice.
- TE Julian Hill (ankle) limited
- C Aaron Brewer (foot/ankle) did not practice. Brewer was seen by local reporters in a boot on Monday.
- RT Austin Jackson (toe) had his 21-day practice window to return from injured reserve opened Wednesday. Jackson, who began practicing as a limited participant, was placed on IR on Sept. 13.
- LB Chop Robinson (concussion) was a full participant in practice.
- CB Rasul Douglas (foot/ankle) DNP
- S Ashtyn Davis (quad) limited
- S Ifeatu Melifonwu (thumb/foot) limited
INJURIES
- QB J.J. McCarthy (right hand) was limited in practice Wednesday. McCarthy practiced with a bandage on his right hand after hitting it on a helmet during Sunday's loss to the Ravens, head coach Kevin O'Connell said. O'Connell told reporters it is not expected to impact McCarthy's prep and McCarthy remains set to play against the Bears.
- RB Aaron Jones (shoulder/toe) limited
- TE Josh Oliver (foot) limited
- C Ryan Kelly (concussion) had his 21-day practice window opened and was a limited practice participant on Wednesday.
- G Will Fries (calf) limited
- OT Christian Darrisaw (knee) was a full participant.
- LB Jonathan Greenard (shoulder) did not practice.
- LB Andrew Van Ginkel (neck) limited
- S Josh Metellus (foot) limited
INJURIES
- RB Terrell Jennings (knee) is questionable to play Thursday against the Jets.
- RB Rhamondre Stevenson (toe) is out for Thursday's game.
- WR Kayshon Boutte (hamstring) out
- TE Austin Hooper (concussion) out
- LB Christian Elliss (hip) out
2-8
INJURIES
- QB Jaxson Dart (concussion) did not practice Wednesday.
- WR Darius Slayton (hamstring) DNP
- TE Daniel Bellinger (groin) was limited in practice.
- OL Evan Neal (hamstring) DNP
- C John Michael Schmitz (shin) limited
- DL Rakeem Nunez-Roches (toe) DNP
- LB Bobby Okereke (shoulder) DNP
- LB Kayvon Thibodeaux (shoulder) DNP
- CB Paulson Adebo (knee) limited
- S Tyler Nubin (neck) DNP
- K Graham Gano (neck) was placed on injured reserve.
DEPTH CHART NEWS
- QB Jameis Winston will start Sunday against the Packers with Jaxson Dart in concussion protocol interim head coach Mike Kafka announced.
COACHING NEWS
- TEs coach Tim Kelly will take over as offensive coordinator, Kafka said. Kafka was promoted to interim head coach from offensive coordinator following Brian Daboll's firing.
2-7
INJURIES
- WR Garrett Wilson (knee) is out for Thursday's game against the Patriots.
- CB Azareye'h Thomas (concussion) out
INJURIES
- OT Lane Johnson (ankle) was a limited practice participant.
- G Landon Dickerson (quad) limited
- G Tyler Steen (oblique) limited
- C Cam Jurgens (knee) limited
- OLB Nolan Smith (triceps) was a full participant.
- CB Jakorian Bennett (pectoral) was activated from injured reserve and a full participant.
RETIREMENTS
- CB Jaire Alexander was placed on the reserve/retired list. Alexander is stepping away from football to get right physically and mentally, NFL Network Insider Mike Garafolo reported Tuesday. The 28-year-old CB will then decide on his playing future after the break, per Garafolo.
INJURIES
- QB Will Howard (right hand) was activated from injured reserve.
- WR Scott Miller (finger) was a full participant in practice Wednesday.
- G Isaac Seumalo (pectoral) was limited in practice.
- OT Broderick Jones (groin) did not practice.
- LB Alex Highsmith (pectoral) DNP
- LB Cole Holcomb (illness) DNP
- CB Darius Slay (concussion) DNP
- CB Cory Trice Jr. (hamstring/knee) DNP
- S Jabrill Peppers (quad) full
SIGNINGS
- CB Asante Samuel Jr. (practice squad)
ROSTER CUTS
- RB Trey Sermon waived
- DB Darrick Forrest (practice squad)
INJURIES
- QB Mac Jones (knee/knee) was a full practice participant.
- QB Brock Purdy (toe) was a limited practice participant on Wednesday. Head coach Kyle Shanahan said Purdy will be "aggressive" with his practice participation.
- WR Ricky Pearsall (knee) returned to practice as a limited participant. Pearsall has not played since the 49ers' Week 4 loss to the Jaguars on Sept. 28.
- DT Alfred Collins (hip) limited
7-2
SIGNINGS
- NT Wy'Kevious Thomas (practice squad)
- CB Mike Reid (practice squad)
INJURIES
- WR Jake Bobo (calf) was listed as a full practice participant for Wednesday's walkthrough.
- WR Tory Horton (groin/shin) was a limited participant.
- TE AJ Barner (calf) full
- G Grey Zabel (heel) limited
- LB Ernest Jones (knee) limited
- DE Leonard Williams (wrist) full
INJURIES
- RB Bucky Irving (shoulder/foot) was listed as limited in Wednesday's walkthrough, indicating his return to practice for the first time since since September. Irving hasn't played since Week 4.
- WR Chris Godwin (fibula) limited
- G Ben Bredeson (hamstring) is "highly unlikey" to play Sunday against the Bills, Bowles said. Bredeson did not practice Wednesday.
- NT Vita Vea (back) limited
- LB Haason Reddick (ankle/knee) DNP
- S Antoine Winfield Jr. (foot) limited
SIGNINGS
- LB Benton Whitley (practice squad)
ROSTER CUTS
- NT Desmond Watson (practice squad)
SUSPENSIONS
- RB Josh Williams was placed on team's reserve/supsended list.
1-8
INJURIES
- WR Calvin Ridley (hamstring) was limited in Wednesday's practice.
- DT Jeffery Simmons (hamstring) did not practice.
- TE Chigoziem Okonkwo (foot) limited
- LB Arden Key (quad) limited
- S Mike Brown (knee) limited
- S Xavier Woods (hamstring) DNP
INJURIES
- QB Jayden Daniels (left elbow) did not practice Wednesday.
- RB Chris Rodriguez Jr. (shoulder) will play Sunday against the Dolphins, per coach Dan Quinn. Rodriguez does not have a designation on the injury report.
- WR Treylon Burks (finger) DNP
- WR Terry McLaurin (quad) will begin his on-field portion of rehab, Quinn said Wednesday from Madrid. McLaurin won't play Sunday against Miami but traveled with the team to Spain.
- LB Frankie Luvu (shoulder) was limited in practice.
- LB Bobby Wagner (thumb) was a full participant in practice.
- S Quan Martin (shoulder) limited
- S Will Harris' 21-day practice window to return from injured reserve was opened and he was a limited participant. Harris was placed on IR with a fibula injury on Sept. 22.