12-5
13-4
- WHERE: Everbank Stadium (Jacksonville, Florida)
- WHEN: 1 p.m. ET | CBS
BILLS
- RB Ty Johnson
- TE Keleki Latu
- OL Tylan Grable
- DT Larry Ogunjobi
- LB Terrel Bernard
- CB Maxwell Hairston
- S Darnell Savage
JAGUARS
12-5
11-6
- WHERE: Lincoln Financial Field (Philadelphia)
- WHEN: 4:30 p.m. ET | FOX
49ERS
- RB Isaac Guerendo
- WR Ricky Pearsall
- WR Jordan Watkins
- DL Kevin Givens
- LB Dee Winters
- LB Luke Gifford
- CB Chase Lucas
EAGLES
- OLB Josh Uche
- QB Sam Howell (emergency third QB)
- CB Jakorian Bennett
- RB AJ Dillon
- OL Brett Toth
- RT Lane Johnson
- DT Ty Robinson
11-6
14-3
- WHERE: Gillette Stadium (Foxborough, Massachusetts)
- WHEN: 8 p.m. ET | NBC
CHARGERS
- CB Isas Waxter
- S Kendall Williamson
- LB Bud Dupree
- LB Kyle Kennard
- OT Austin Deculus
- WR Dalevon Campbell
- TE Tyler Conklin
PATRIOTS
- WR Jeremiah Webb
- LB Bradyn Swinson
- OT Marcus Bryant
- G Caedan Wallace
- TE CJ Dippre
- DT Khyiris Tonga
- QB Tommy DeVito (emergency third QB)