Wilkerson underwent ankle surgery Sunday, a procedure that followed his gruesome injury suffered in a loss to the Redskins, and one that required an overnight stay in a Washington, D.C., hospital.
At the time, Packers coach Mike McCarthy called the injury "significant," and NFL Network Insider Ian Rapoport reported the injury was likely a season-ending one. That's now the case with Saturday's announcement.
Elsewhere in injury news:
- Broncos cornerback Tramaine Brock (thigh) is doubtful, while cornerback Adam Jones (thigh), linebacker Brandon Marshall (knee) and safety Dymonte Thomas (abdomen) are questionable.