NFL Network Insider Ian Rapoport reports Darnold, who sat out Wednesday's practice and is currently in a walking boot is dealing with an injured foot, which will sideline him for Sunday's game against the Buffalo Bills.
Rapoport adds Darnold will be re-evaluated on a week-by-week basis following the team's Week 11 bye.
Jets coach Todd Bowles clarified that Darnold is dealing with a foot strain and the team will monitor his progression throughout the week before making a determination on Sunday.
The No. 3 overall pick took a beating in the Jets' Week 9 loss in Miami and said after the game that he got dinged up.
"Yeah, I feel fine, some bumps and some bruises, but everything is good," Darnold said on Monday, via Manish Mehta of the New York Daily News.
By Wednesday he was in a walking boot.
The youngest NFL quarterback to ever start a season opener has meandered his way through an up-and-down season. At times, he looks like a wunderkind, effectively dodging rushers and making pinpoint throws. At others, he's struggled to see defenders, throwing 14 interceptions through nine games.