Wake sprained an MCL during the Dolphins' 27-23 win over the Atlanta Falcons, NFL Media Insider Ian Rapoport reported Monday, per a person informed of the injury. Wake will miss the Dolphins' Week 4 game, and then the team will see how his body responds, according to Rapoport.
The South Florida Sun Sentinel first reported the news.
Wake was injured during Miami's first defensive series and was replaced in the lineup by Derrick Shelby. Dion Jordan, the No. 3 overall pick in April's draft, also is expected to see an increase in playing time during Wake's absence.
Both Shelby and Jordan are capable replacements who show off Miami's depth, but Wake still will be sorely missed. That starts next Monday night, when the Dolphins put their undefeated record on the line against Drew Brees and the New Orleans Saints.