NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

Does your fantasy team need help at a position or two to keep your championship hopes alive? You've come to the right place! Matt Okada provides a list of widely available players to target on the waiver wire, including six running backs.

NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

How will Trey Lance stack up against the other San Francisco 49ers quarterbacks in training camp? Kevin Patra spotlights the 10 most intriguing position battles to track as teams prepare for the 2023 NFL season.

NFL.com keeps you up to date with all of the latest league news from around the NFL. Visit NFL.com's transaction hub for a daily breakdown.

Can the Eagles improve their No. 5-ranked rushing attack? Maurice Jones-Drew spotlights three teams who will be looking for a new primary RB in 2023. Plus, there's a new No. 1 at the top of his RB rankings.

Will someone emerge from the Lions' QB2 battle on Sunday against the Steelers? Eric Edholm spotlights one thing to watch on each of the 32 teams in Week 3 of the preseason.

49ers WR Deebo Samuel suffered a groin injury against the Vikings. Plus, other news from around the NFL on Sunday.

It will be next running back up for the 49ers. Standout rookie running back Eljiah Mitchell is inactive for Sunday's game against the Jaguars due to a broken finger. 

Michael F. Florio breaks down which players you should target on the waiver wire ahead of Week 8 of the 2021 NFL Fantasy Football season.

NFL.com's Michael F. Florio breaks down the best and toughest fantasy matchups for Week 7 of the 2021 NFL season.

All the answers you're looking for about your lineup questions. Check out the latest in the Start 'Em, Sit 'Em 2021 NFL Fantasy football league.

NFL.com's Michael F. Florio's breaks down the best and toughest fantasy football matchups in Week 4 of the 2021 NFL season.

Michael F. Florio breaks down which players you should target on the waiver wire ahead of Week 3 of the 2021 NFL season.

49ers running back Raheem Mostert announced on Twitter Tuesday that he is set to undergo season-ending surgery to repair his knee.

You have lineup questions. We have answers. At least we hope. Start 'Em, Sit 'Em is back for the 2021 NFL season.

Lance Zierlein identifies one pivotal rookie for each of the 32 NFL teams, a list that includes only one of the five quarterbacks selected in the first round of this year's draft.

What did we learn about each NFC team in the first full week of preseason action? Gregg Rosenthal provides everything you need to know, including an evaluation of Jordan Love's first NFL game action.

Will Matthew Stafford deliver for the Rams? Can a healthy Nick Bosa get the 49ers back on track? Adam Maya provides a training camp preview for the NFC West, with position battles and key players to watch across all four rosters.

After an injury-riddled 2020 season, the San Francisco 49ers are back with a roster that appears loaded on paper. Can Kyle Shanahan get them back to the Super Bowl? Adam Rank examines the state of the franchise ahead of the 2021 campaign.

Which rookie running backs are poised to enjoy immediate NFL success? After crunching the numbers, analytics guru Cynthia Frelund ranks the top five newbies by potential production in the 2021 season.

Since divisional realignment back in 2002, we've only experienced two NFL seasons in which at least one team didn't go from worst to first. Who could accomplish the feat in 2021? Adam Schein ranks the eight candidates.

Which roster looks best in the NFL's toughest division? Is the Rams' top-heavy blueprint built for success? Can the 49ers return to the Super Bowl with a rookie at quarterback? Gregg Rosenthal projects the starters for every team in the NFC West.

How did each team in the highly competitive NFC West perform in the 2021 NFL Draft? Did the 49ers' do the right thing at No. 3? Will the Rams' historic gamble pay off? Gennaro Filice has the division's report card.

Indianapolis Colts running back Trey Sermon 27-yard scamper marks the longest of his career.

Watch all of the highlights from the Indianapolis Colts and Philadelphia Eagles highlights from Preseason Week 3 of the 2023 NFL season.

Watch all of the Philadelphia Eagles' top plays from their game against the Indianapolis Colts in Preseason Week 3 of the 2023 NFL season.

Philadelphia Eagles running back Trey Sermon stumbles across the goal line for an opening-drive touchdown.

Watch all of the Philadelphia Eagles' top plays from their game against the Cleveland Browns in Preseason Week 2 of the 2023 NFL season.

Watch all of the highlights from the Cleveland Browns and Philadelphia Eagles from their game in Preseason Week 2 of the 2023 NFL season.

Philadelphia Eagles running back Trey Sermon hits cutback lane with FURY for 33-yard touchdown.

Watch the best plays by the Philadelphia Eagles in Preseason Week 1 against the Baltimore Ravens.

Watch the highlights from the Preseason Week 1 game between the Philadelphia Eagles and the Baltimore Ravens.

Philadelphia Eagles running back Trey Sermon barrels in the end zone for 2-yard touchdown.

Philadelphia Eagles quarterback Jalen Hurts dekes Jacksonville Jaguars linebacker Josh Allen perfectly, and hands to Eagles running back Trey Sermon for a 14-yard gain.

Watch the San Francisco 49ers best plays from the first four weeks of the 2021 season.

NFL analyst Brian Baldinger breaks down how San Francisco 49ers quarterback Jimmy Garoppolo set up his team for success in Week 3 despite their loss to the Green Bay Packers.

Watch all of the highlights from the Green Bay Packers and San Francisco 49ers from their Week 3 matchup on "Sunday Night Football" in the 2021 NFL regular season.

San Francisco 49ers rookie running back Trey Sermon dives across the plane for his first career NFL touchdown.

NFL Network's Marcas Grant shares the top four sneaky fantasy starts for Week 1.

NFL Network's Patrick Claybon, Marcas Grant, Michael F. Florio and Adam Rank examine crowded running back rooms in fantasy football for 2021.

NFL Network's Adam Rank and Michael F. Florio highlight four players to stash and hold in fantasy leagues in 2021.

Watch highlights from the Preseason Week 3 matchup between the Las Vegas Raiders and the San Francisco 49ers.

Watch the San Francisco 49ers' top plays vs. Las Vegas Raiders during Preseason Week 3.

NFL rookies guess their "Madden NFL 22" rating.

NFL Network's Cynthia Frelund's top three rookie running backs entering 2021.

Watch all the highlights from 2021 NFL rookie minicamps.

NFL Network's Adam Rank shares his must-draft players to win your fantasy league in 2021.

NFL Network's Bucky Brooks and Lance Zierlein grade the San Francisco 49ers' 2021 NFL Draft class.