Seantrel Henderson suspended four games by NFL

The Buffalo Bills have endured a mountain of injuries and off-the-field issues this offseason. It's not over yet.

Bills offensive tackle Seantrel Henderson was officially suspended by the NFL for the first four games of the 2016 season for violating the NFL Policy and Program for Substances of Abuse, the team announced Friday.

Henderson dropped his appeal on Friday.

The third-year lineman is battling Crohn's disease and tested positive for marijuana. Henderson underwent two surgeries on parts of his intestines during the offseason.

"Although grossly unfair, we decided it was best to not appeal," Henderson's agent, Brian Fettner, said in a statement obtained by NFL Network Insider Ian Rapoport. "Seantrel has Crohn's Disease and had two life-threatening, major intestinal, offseason surgeries. The only known treatment is cannabis. There is zero allowable medical exemption for this per the NFL; however, there clearly should be."

Henderson is eligible to return to Buffalo's active roster following the team's Oct. 9 game against the Los Angeles Rams.

This isn't the first time Henderson has been suspended because of marijuana. During his playing days at the University of Miami, he was suspended by the team three times and admitted he "got in trouble a couple times for marijuana."

Henderson returned to Bills practice on Tuesday, which coach Rex Ryan called a "big step," while noting that Henderson was no sure bet to play in Sunday's opener against the Ravens.

Henderson is now out, leaving the Bills to start Jordan Mills across from reliable bookend Cordy Glenn.

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