INDIANAPOLIS -- Colts defensive end Robert Mathis practiced for the first time this week and is listed as questionable for Sunday's game against the Denver Broncos.
A Pro Bowl selection last season, Mathis missed practice Wednesday and Thursday with a quadriceps injury before returning Friday.
Right tackle Ryan Diem also is questionable after missing his second consecutive day of practice with a hamstring injury. Left tackle Charlie Johnson returned to practice after missing last weekend's game with a foot injury and is listed as questionable.
Four players have been ruled out of the game: running back Donald Brown (chest), safety Aaron Francisco (ankle), wide receiver Anthony Gonzalez (knee) and kicker Adam Vinatieri (knee).
Copyright 2009 by The Associated Press