Next Gen Stat: Buffalo's wide receivers averaged 3.3 yards of separation on targets in Week 11 (3rd-most in NFL). Heading into Week 11, the Bills had an overall average of 3.0 yards of separation per target (also 3rd-most in NFL).
Run-heavy offense: The Bills run the ball on 47.7 percent of offensive plays (2nd-most in NFL) and they average a league-best 5.3 yards per carry.
Will Shady play: LeSean McCoy had surgery on his injured thumb on Sunday night. He was limited in practice on Wednesday and Thursday, and he's officially ruled questionable.