Game facts: Bills at Patriots

No-win zone: The Bills have lost 14 of their 15 games in New England since 2001. The lone Bills win came in Week 17, 2014 -- when the Patriots rested players after clinching a No. 1 seed.

Home-field advantage: The Patriots are 28-2 at home since 2013 (including playoffs).

Run-heavy offense: New England has the highest rush percentage (54.0) in the NFL this season. The Bills feature the strongest run defense that the Pats have faced yet, allowing just 3.4 yards per carry (T-4th in NFL).

Bend-but-don't-break defense: The Patriots have allowed 5.7 yards per play so far this season (20th in NFL), but they have surrendered just 15 PPG (5th in NFL).