Chris Wesseling built a defensive All-Pro team with his seasoned eye, while Nick Shook studied the Next Gen Stats. See where they agree (Aaron Donald) and differ (Grady Jarrett).

Week 5 is here! Check out the full tally of the official injury report and gameday designations for all 13 Sunday games.

Can Nick Foles reinvigorate the Jaguars? Are we about to finally witness peak Andrew Luck? Is Marcus Mariota a franchise quarterback? Who's in charge in Houston? Gennaro Filice previews training camp across the AFC South.

Texans running back Lamar Miller (ankle) has been downgraded to out for Sunday's game against the Eagles. Miller was limited in practice the past two days. Plus, other injuries we're tracking on Friday.

Tom Brady and the New England Patriots (3-2) held off a fourth-quarter comeback and made history in the process on Thursday evening, defeating the Indianapolis Colts, 38-24, to kick off Week 5.

The Packers will be without their top three wide receivers Davante Adams, Randall Cobb and Geronimo Allison at practice Thursday. Plus other injuries we're tracking around the NFL.

After starting eight QBs over three years, Houston finally found its guy in Deshaun Watson. Nick Shook provides rookie grades and offseason game plans for each AFC South team.

The Giants, already without receivers Odell Beckham and Brandon Marshall, will now be missing several more starters when they play at Denver on Sunday night. Here is a list of injury updates.

Indianapolis Colts coach Chuck Pagano is feeling pretty good about his defensive line these days, particularly the team's interior players.

The Colts' offseason overhaul included massive upgrades to the defensive front seven. One of those being Johnathan Hankins, who believes the Colts can be one of the best units in the AFC in 2017.

The Indianapolis Colts defense stuffs Carolina Panthers rookie quarterback Will Grier's fourth-down QB sneak for a turnover on downs.

Welcome to the league, rook! Carolina Panthers rookie quarterback Will Grier tosses his first career interception to Indianapolis Colts defensive back Anthony Walker.

Watch the highlights as the Indianapolis Colts take on the Jacksonville Jaguars in Week 13.

Watch highlights from the Week 3 matchup of Indianapolis Colts versus the Philadelphia Eagles in Carson Wentz's first game of 2018.

Indianaplos Colts linebacker Anthony Walker jumps Philadelphia Eagles quarterback Carson Wentz pass for interception.