The team previously listed the starting quarterback as doubtful to play in L.A., but downgraded him to out on Saturday. Wentz is suffering from a fracture in his back, NFL Network Insider Ian Rapoport reported Thursday.
This development jives with Rapoport's reporting earlier in the week that Wentz was not expected to play. The QB sat out practice all week.
The Eagles performed CT scans on Wentz's back throughout the season, according to Rapoport, but none revealed the fracture until now. The quarterback will not need surgery, but could be shut down for the remainder of the season.
Philadelphia (6-7) is in the hunt for the sixth seed in the NFC, but its playoff hopes could take a dip if Wentz is sidelined for more than just Sunday's game.
Here are the other injuries worth monitoring in Week 15:
- Houston Texans running back Lamar Miller suffered an ankle injury during the first quarter of Saturday's 29-22 win over the New York Jets and didn't return to the game. Texans coach Bill O'Brien said after the game he didn't believe the injury is serious. Defensive tackle Brandon Dunn also left early with an ankle injury.
- New York Jets receiver Rishard Matthews suffered a hamstring injury in Saturday's loss to the Texans. Offensive tackle Brandon Shell was carted off with a knee injury and didn't return. Jets coach Todd Bowles said after the game the team isn't sure about extent of Shell's injury. He will undergo an MRI on Sunday, Bowles said.
Defensive tackle Kawann Short (calf) is listed as doubtful. Coach Ron Rivera told reporters the team won't know Short's availability until Monday morning.
- The Pittsburgh Steelers activated wide receiver Eli Rogers (ACL) to the 53-man roster. In a corresponding move, Pittsburgh placed tackle Marcus Gilbert (knee) on season-ending injured reserve.