McCoy suffered a hamstring strain in the first quarter he is now considered day-to-day, NFL Network Insider Ian Rapoport reported. His availability will be watched closely throughout the week, Rapoport notes.
McCoy, 30, has endured a tough season from a statistical standpoint. One season removed from a 1,000-yard rushing campaign, McCoy has 479 yards on 145 carries in 12 games this season, averaging a career-low 3.3 yards per attempt. The 10th-year pro has just one 100-yard rushing effort in 2018, which came in Week 10, and he has failed to top 30 yards rushing in a game six times this season.
Other injuries we're monitoring on Monday:
Harbaugh also gave an update on the status of Joe Flacco, who's been sidelined for a month with an injured hip. "I think it stands to reason that if Joe is ready to go, he'll be part of the game plan" Sunday vs. the Bucs.
- Philadelphia Eagles running back Corey Clement is believed to have a suffered knee sprain and will have an MRI today to confirm, Rapoport reported. Coach Doug Pederson said Clement will have further testing done. The Eagles are expected to sign running back Boston Scott off the Saints practice squad to fill in for Clement, Rapoport reported.
Pederson said guard Isaac Seumalo (pec) is "day to day." The team is awaiting an MRI on defensive end Josh Sweat, who suffered an ankle injury Sunday.
- New York Giants coach Pat Shurmur said wide receiver Odell Beckham, who is dealing with a bruised quad, is feeling much better Monday. "We'll see where that takes us," he said.
- Redskins tight end Jordan Reed, who suffered a foot sprain in Sunday's loss, is having a precautionary MRI, Rapoport added. Coach Jay Gruden specified that Reed is dealing with a sprained big toe, and there is concern the injury could sideline him for the rest of the season.
- Arizona Cardinals coach Steve Wilks said defensive tackle Robert Nkemdiche is going on injured reserve for a knee injury that will require surgery.
- San Francisco 49ers coach Kyle Shanahan said wideout Pierre Garcon is heading to injured reserve. He will undergo arthroscopic surgery on his knee.
- Los Angeles Rams running backMalcolm Brown (shoulder) will eventually go on injured reserve, coach Sean McVay said.