Gordon was suspended one season after his appeal was denied on Aug. 27 for violating the league's substance-abuse policy.
No special exception would be made for Gordon. Under the new rules, 10 games is the standard ban for a fourth violation of the NFL's policy on substances of abuse.
The star wide receiver could end up facing another suspension pending the outcome of his November hearing for a DWI arrest in July.
Gordon was the NFL's leading receiver last season, setting a franchise record with 1,646 yards despite subpar quarterback play.
If the Browns are still in the AFC North race, Gordon's presence would have the potential to catapult his team into the playoffs. If the season takes a turn for the worse over the next two months, Gordon would likely be catching passes from first-round rookie Johnny Manziel, providing Browns fans with a glimpse of a more exciting future.