However, it doesn't look good for running back Ahmad Bradshaw.
In his place, Brandon Jacobs would get the start and shoulder the load, with D.J. Ware spelling him in certain situations.
Jacobs said he was pleased with how he played last week against the Patriots after rushing for 72 yards and a touchdown on 18 carries.
"I felt I got into some kind of a rhythm," Jacobs said, according to the team's website. "I can't get into a rhythm being in, out, in, out, in another play here, next play, next two series, whatever. I have to keep going and be able to get some continuous plays."
Nicks has 38 receptions for 575 yards with three touchdowns in seven games this season.