Everything you need to know as kickoff approaches...
Key game-time decisions
Harrison: Week 12 predictions
All players questionable unless noted
Bruce Arians said it was "iffy" that Fitzgerald would play this week in Seattle. The receiver missed practice all week while nursing a Grade 2 MCL sprain.
Sanders cleared protocol and appears in line to play. Ware came down with an illness and was added to the injury report on Saturday.
Bush was limited all week after missing last Sunday's game with an ankle injury he's been hobbled by for several weeks this season. UPDATE: He is not expected to play Sunday, according to Rapoport.
Both wideouts practiced fully on Friday and appear good to go.
The tight end was limited Thursday and Friday.
Martin has missed the past three games and was limited in practice Thursday and Friday. Sims was limited as well this week, but appears in line to start. David also was limited Thursday and Friday. Verner, however, missed both the final two practices of the week.
Hunter was full-go Thursday and Friday.
The running back is expected to play for the first time since Week 7. Khiry Robinson, on the other hand, was declared out.
Jackson says he feels good after missing last week's game.
Rain is the precipitation of choice for Mother Nature this Sunday.
Bucs at Bears - 50 degrees / Rain (80 percent; 15 mph winds)
Packers at Vikings -- 40 degrees / Chance of rain (39 percent)
Dolphins at Broncos -- 40 degrees / Winds (20 mph)
Cardinals at Seahawks -- 50 degrees / Slight chance of rain (15 percent)
Cowboys at Giants -- 43 degrees / Chance of rain (5 percent at kickoff, increasing probability as the game wears)
*Forecasts courtesy of Weather Underground
Three matchups to watch
Brooks: Primed to perform
Which players are in position to go off during Week 12's game action? Bucky Brooks provides his scouting eye. READ
This game will pit the Seahawks' No. 1 rushing offense against the Cardinals' No. 3 ranked rushing defense. The Seahawks are first in yards per rush (5.5) and second in rushing touchdowns (14). Marshawn Lynch will slam into Todd Bowles' front led by Calais Campbell, who is having an All-Pro-type of season -- the winner of this battle will control the game. The Cards could hold the edge against a Seahawks offensive line that has struggled throughout the season and dealt with injuries. If Arizona consistently collapses Seattle's line, it will be a long day for Lynch, Russell Wilson and the rest of a lopsided offense.
Let's not slow-play it: The Browns get back their best playmaker and a game-changer on offense. His presence completely changes what the Browns can do offensively and how defenses dispense personnel. The wideout led the NFL last year with 30 receptions of 20-plus yards. Even without an obvious deep threat, the Browns have the third-most plays from scrimmage of 20-plus yards (49). Brian Hoyer is going to take his shots deep. Trufant has been the lone stalwart in Atlanta's secondary this season. He has been stellar at closing on passes and can play the ball in the air (Pro Football Focus ranks him their fourth-rated corner for the season). Our "Making the Leap" candidate will have a size disadvantage, but with Robert Alford out for the Falcons, he'll be the only cornerback who can come close to matching up with Gordon.
The Chargers' playoff hopes are on the ropes as we hit Week 12. San Diego's offensive line has allowed Philip Rivers to be punished. With a running attack that hasn't given him much help, it'll be on Rivers' shoulders to carry the load against a Rams defensive line that has swarmed the quarterback recently. Watch the middle, where Rams rookie defensive tackle Aaron Donald hasn't gotten nearly enough attention for Defensive Rookie of the Year. He's been dominant at pushing the pocket and getting off blocks. With Chargers center Rich Ohrnberger not expected to play, rookie Chris Watt appears set to make his first career start at center. If Rivers is pressured up the middle, it could be another rough day for the quarterback and his injured ribs.
Did You Know?
Where is Atlanta's explosive offense? Outside of their 56-point explosion in Week 3, the Falcons are only averaging 20.2 points per game (which would be only 23rd in the NFL).
Lovie Smith, who coached the Bears from 2004-2012, will be the seventh coach since 2000 to coach against a team for which he spent at least nine seasons. The other coaches are 2-4 in their first game versus their former team. Andy Reid and John Fox recorded victories; Jeff Fisher, Mike Shanahan, Dennis Green and Marty Schottenheimer recorded losses.
The Legend of Mike Evans: Last Sunday, on a single drive that spanned the third and fourth quarters, Evans had four catches for a total of 104 yards. How is that possible, given that the drive started at the Tampa 20-yard line? The Bucs committed two penalties on the drive and had one rush for -4 yards, which translated to -24 yards. No other NFL player in the past 30 years has gained as many as 100 yards -- rushing and/or receiving -- on one drive.
Bears' opponents have reached the red zone 44 times, most in the NFL and are averaging 6.04 yards per play, second most in the NFL. Chicago is also giving up 29.0 points per game, most in the NFL.
The Bengals' D has allowed 24-plus points in six of their last seven games after allowing a total of 33 points in first three games this season.
The Texans have rushed for 115-plus yards in nine of 10 games this season and have 300-plus yards of total offense in all 10 games this season.
The Jags have allowed 39 QB sacks this season (most in NFL) and could come close to breaking the franchise record (63) set in 2001 with Mark Brunell and Jonathan Quinn.
Aaron Rodgers' third-down passer rating of 126.7 is the highest in the NFL. How do you get an offense off the field when the quarterback is tossing for 11 touchdowns and 732 yards on 77 third-down attempts? HOW???
Watch Melissa Stark's sit-down with Bill Belichick on Sunday's NFL GameDay First (7 a.m. ET) and NFL GameDay Morning (9 a.m.).
Mark Sanchez is coming off consecutive 300-yard games for the first time in his career. The 678 yards in the last two games is Sanchez's highest two-game total of his career.
Philadelphia has 100-plus rushing yards in five of last six games. Tennessee has allowed 100-plus rushing yards in eight of its last nine games.
Last time the Cardinals owned the best record in the NFL after Week 11 or later was at the end of the 1948 season (11-1).
Seattle boasts the NFL's best rushing offense (174.2 YPG) but the 30th ranked passing offense (191.8 YPG).
The Seahawks are 5-0 when they hold opponent to 20 points or fewer this season -- 1-4 when opponents score more than 20 points.
Just 32.1 percent of the Chargers' rush attempts have gone for 4 or more yards (lowest percent in the NFL).
Forty-nine Dolphins drives have reached the red zone this season, most in NFL. They have scored on 37 red-zone drives (22 TD, 15 FG) but have three red-zone picks (T-most in NFL with TB, PIT and NYG).
The Dolphins' defense is ranked fourth in points per game, second in total yards per game allowed, eighth in rushing yards allowed, second in pass yards and sixth in takeaways (all better than last season). The Dolphins are also allowing just 19.0 percent of 20-plus air yard passes to be completed (lowest in the NFL).
The Broncos rank fifth in points per game (29.3), third in yards per game (412.9), second in passing yards per game (323.0) and first in yards per play (6.2).
Washington has allowed seven drives of 10-plus plays, fewest in NFL. San Francisco has 21 drives of 10-plus plays, T-eighth in NFL.
San Francisco has 100-plus rushing yards in three of four home games. Washington has allowed 100-plus rushing yards in three of five road games.
This season, Michael Vick has completed just 22.6 percent of 10-plus air yard passes (seven of 31 -- lowest in the NFL among QBs with at least 20 such attempts).
Baltimore's offense has allowed 14 sacks this season (T-fourth best in NFL). New Orleans' defense has 16 sacks in their last five games.