It was over when ...
The Bills turned the ball over on downs as quarterback J.P. Losman was sacked and threw two incompletions on Buffalo's final possession.
Are Buffalo's playoff hopes finished? Is [Shaun Hill](/player/shaunhill/2504833/profile) the answer at QB for the Niners? [ **What are your thoughts?**](http://www.nfl.com/gamecenter/fanfeedback?game_id=29707&displayPage=tab_fan_feedback&season=2008&week=REG12&override=true)
Losman started the second half for the Bills due to a groin injury sustained by starter Trent Edwards. Losman finished 11-of-17 with 93 yards. ... 49ers WR Isaac Bruce's first-quarter touchdown was the 90th of his career. ... San Francisco's win prevented the Arizona Cardinals from clinching the NFC West. ... Bills RB Marshawn Lynch finished with a season-high 134 yards rushing on 16 carries.