» Last meeting: David Garrard had a rushing touchdown to lead Jacksonville past San Francisco, 10-9, on Dec. 17, 2005.
» Streaks: The Jaguars have won both meetings against the 49ers.
» Last week: Jacksonville rallied for a late touchdown to beat Buffalo, 18-15. ... San Francisco's comeback attempt fell short in Green Bay as the Niners lost, 30-24.
Keep your eye on ...
The Jags' defensive discipline: Despite its 23rd overall ranking, Jacksonville has played some solid defense at times this year. The problem is that the Jaguars are known to go through lapses on that side of the ball. If they fall asleep against the 49ers, Frank Gore has the explosion to make them pay with a long run or two.
Mike Singletary's response: The 49ers have gone just 1-5 since a 3-1 start, and are now on the outside fringes of the playoff chase. Singletary got the team on a roll at the end of last season, and he will have to work similar magic this year if San Francisco wants to have any chance of making the postseason.
Did you know?
This will be Jacksonville's first-ever trip to San Francisco. ... The Jaguars have not had an 800-yard receiver since 2005. Mike Sims-Walker is 106 yards away from the number this year. ... When Alex Smith has at least a 95 passer rating, the Niners are 5-0. ... San Francisco's Vernon Davis is tied for second in the NFL with eight touchdown catches.