Cherilus, a native of Haiti, started 37 consecutive games at right tackle before switching to the challenging left tackle position as a senior.
He is considered to have limited change-of-direction agility, but overall has a solid reputation as strong run-blocker.
Scouts say he is a tireless worker who could join the long line of productive Boston College offensive linemen who have played in the NFL.
Detroit also needs help at linebacker, running back and defensive end. The Lions' other first-day pick was the 14th pick of the second round (No. 45 overall).
Pearson, a safety, was arrested Saturday in Florida on domestic violence charges.
He was charged with aggravated battery on a pregnant woman and domestic battery by strangulation, both felonies, according to an arrest report from the Hillsborough County sheriff's office.
He also was charged with obstructing or opposing an officer without force, a misdemeanor, and was being held without bail in a Tampa jail.
It was not immediately known if Pearson had an attorney.
"We are aware of the situation with Kalvin Pearson, and we are gathering information," the Lions said in a statement. "We will have no further comment today."
Pearson, who is in his fourth NFL season, led the Buccaneers in special teams tackles in 2007, with 21, and appeared in all 16 games in 2007.
Copyright 2008 by The Associated Press