Gurley, who was held out of preseason games last season as a rookie while recovering from a torn ACL, rushed for 20 yards on four carries and scored on a 3-yard run.
The No. 1 overall draft pick mostly struggled for the second consecutive week despite working with the first-unit offensive line for two series. Goff lost a fumble after tripping over left guard Cody Wichmann and fumbled out of bounds while being sacked.
Goff's first touchdown pass came on a 10-yard throw to Brown, who made a juggling catch to put the Rams ahead early in the fourth quarter. Goff played the entire second half and finished 8 of 12 for 82 yards.
Copyright 2016 by The Associated Press