The Colts decided Saturday that Mathis and safety Antoine Bethea would not play against the Raiders, Indianapolis spokesman Craig Kelley said. The team had already listed receiver Marvin Harrison (bruised left knee), defensive tackle Raheem Brock (ribs) and right tackle Ryan Diem (knee) as out for Sunday's game.
Mathis (sprains to both knees) and Bethea (sprained left knee) were injured during last Sunday's 44-20 victory in Baltimore. Neither finished the game, in which the Colts pulled most of their starters midway through the third quarter.
Rookie Ed Johnson has been the starter since McFarland was injured during training camp.
Copyright 2007 by The Associated Press