Everything you need to know as kickoff approaches...
Key game-time decisions
All players questionable unless noted
Newton was a full participant in Friday's practice. Coach Ron Rivera spoke optimistically, but Newton will be a true game-time decision. UPDATE: Rivera is considering holding Newton out to help him get healthy for the next 15 games, NFL Media Insider Ian Rapoport reported Sunday. Newton feels good, and players think he's ready to play, but Rivera might err on the side of caution with the star QB, per Rapoport.
Brady mysteriously missed practice Thursday and was limited Friday. We fully expect him to be fine.
Orakpo is on the record saying he'll be ready to go. Reed participated in practice Wednesday, Thursday and Friday. He also plans to be ready. UPDATE: NFL Media's Albert Breer reported Sunday that Orakpo and Reed are a go baring a pregame set back.
Harrison: Week 1 predictions
With the 2014 season upon us, Elliot Harrison unveils an upset-rich slate of picks. Who will be shocked in Week 1? READ
Crabtree said he was good to go after missing practice Wednesday and being limited Thursday and Friday.
The wideout was limited Friday, but expected to be fine.
Graham is a true game-time decision. If the starter can't go, rookie C.J. Fiedorowicz will get the nod.
Gates appeared on the injury report for the first time after practice Saturday.
Three matchups to watch
Colin Kaepernick looked terrible this preseason, However, this is no time to panic. It's never pretty when your offensive line is in flux and your starting running back barely plays. I want to see Kap get in a groove against a Cowboys defense absent of any playmakers. After departures, injuries and suspensions, Dallas is without players who accounted for 54 starts, 19 sacks, 244 tackles, 7 interceptions and 31 QB hits in 2013. If Kaepernick performs poorly Sunday, we'll revisit the panic button.
The one starting rookie quarterback is greeted by a secondary that would get made fun of on the island of misfit toys. If Carr can withstand the Rex Ryan pressure packages, he could be in for a good first outing. Imagine if Carr goes into MetLife Stadium and lights it up. Both the acute joy from Raiders fans and apocalyptic mayhem in New York would be awesome to watch. It's too bad we can't enforce an edict that the losing team in this game is required to fire its coach. Imagine the never-ending stream of zero-coverage blitzes Rex would bring if he was standing underneath the guillotine.
If Cam plays, we will fear for his safety throughout. The Panthers' signal caller is dynamic because of what he can do with his feet and strength. If SuperCam's powers are diminished or play-calling completely restricted he could be a sitting duck. McCoy has been dynamic in Lovie Smith's defense. He'll face a revamped Panthers offensive line and a less than mobile Newton. This might not end well for Newton.
Did you know?
In 2013, eight of the 12 teams that reached the playoffs won in Week 1. Two of the four who lost fell to other playoff teams (GB lost to SF; CAR lost to SEA)
Matt Forte took 71.5 percent of his team's rush attempts in 2013, by far most in the NFL. He was the only player with over two-thirds of his team's rush attempts.
Tom Brady has thrown one or fewer interceptions in 17 straight games. He has thrown more than two picks once in his last 105 games -- four picks, Week 3, 2011 at Buffalo.
During his time with Pittsburgh, Mike Wallace caught 43 percent of passes thrown 40-plus yards in his direction. However, with Miami in 2013 he caught just 17 percent of passes thrown 40-plus yards downfield.
The Raiders have lost their last 13 games at 1 p.m. in the Eastern Time zone. Their last win came in 2009, Week 13 at Pittsburgh.
Jets Total Defense since 2009 (yards per game/NFL rank)
2009 252.3 1st
2010 291.5 3rd
2011 312.1 5th
2012 323.4 8th
2013 334.9 11th
The Jags recorded just 31 sacks in 2013, tied for last in the NFL. It was the second straight season they've been at the bottom and finished 25th or worse in sacks in five straight seasons.
The Browns have lost nine straight season openers -- tied for the longest streak in NFL history. They last won their opener with Jeff Garcia at quarterback (2004 vs BAL).
The Vikings have not had a QB throw for 3,000 yards in a season since Brett Favre (4,202 yards in 2009). All 31 other teams have had at least one such passer since 2010.
Cumulatively, the Rams' receivers group has just three receiving touchdowns in 80 of their last 82 individual games:
Tavon Austin: 2 TD in last 11 games
Brian Quick: 1 TD in last 10 games
Chris Givens: 0 TD in 21 straight games
Stedman Bailey: 0 TD 16 career games
Kenny Britt: 0 TD in 13 straight games
Austin Pettis: 0 TD in 11 straight games
Jim Harbaugh has a 41-14-1 record including playoffs, which is the second-most wins by any coach in his first three seasons, including playoffs (George Seifert, 42-11).
In 2013, Cam Newton completed just 20 percent of passes thrown 20-plus yards in the air, the lowest percentage in the NFL (min. 40 attempts).
Each time LeBron James has lost in the NBA Finals, the Giants have gone on to win the Super Bowl that season:
2007: Spurs defeat LeBron's Cavaliers -- NYG win Super Bowl vs NE; 2011: Maverick's defeat LeBron's Heat -- NYG win Super Bowl vs NE; 2014: Spurs beat LeBron's Heat 4 games to 1 -- Super Bowl TBD
The Cardinals' offense has allowed one or more sacks in 51 straight games, the longest active NFL streak.