McNabb has been sidelined since spraining his right ankle and injuring his thumb in a win over the Miami Dolphins on Nov. 18.
A.J. Feeley is expected to get his second consecutive start in place of McNabb. Feeley is coming off a strong outing in a 31-28 loss to New England in which he had career bests in completions (27) and yards passing (345) and threw for three touchdowns. But he also had three interceptions, including one that was returned for a score.
McNabb has thrown the ball on the side and was scheduled to work with trainers again after practice Friday, but he didn't participate with the team.
The Associated Press contributed to this report.