Paying no mind to a penalty that pushed the spot back 15 yards, [Josh Brown](/player/joshbrown/2505459/profile) hits a 49-yard field goal to give the [Rams](/teams/st.louisrams/profile?team=STL) their first win.
Facing a fourth-and-two situation with seven seconds remaining, [Matt Schaub](/player/mattschaub/2505982/profile) takes the ball in himself to give the [Texans](/teams/houstontexans/profile?team=HOU) their first win.
How did the [Falcons](/teams/atlantafalcons/profile?team=ATL) manage to win after allowing a go-ahead score to the [Bears](/teams/chicagobears/profile?team=CHI) with 11 seconds left? Find out with this can't-miss comeback.
The [Dolphins](/teams/miamidolphins/profile?team=MIA) use the single-wing "Wildcat" offense once again to create a big play, as Chad Pennington hits Patrick Cobbs for a 53-yard score.
Not to be outdone by the "Wildcat," [Jacoby Jones](/player/jacobyjones/2495651/profile) gives the [Texans](/teams/houstontexans/profile?team=HOU) their own can't-miss highlight on this kickoff return for a touchdown.
Oshiomogho Atogwe picks up a fumble after a lineman attempts to run with the ball and returns it for a key score in the [Rams](/teams/st.louisrams/profile?team=STL)' upset of the [Redskins](/teams/washingtonredskins/profile?team=WAS).
J.J. Arrington electrifies the University of Phoenix Stadium crowd by returning the opening kickoff 93 yards for a touchdown.
Trailing 24-14 with just over two minutes left in the game and in need of a score, Marion Barber 70 yards on a short pass from [Tony Romo](/player/tonyromo/2505354/profile).
For the first time in NFL history, an overtime game is won on a blocked punt as the [Cardinals](/teams/arizonacardinals/profile?team=ARI) beat the [Cowboys](/teams/dallascowboys/profile?team=DAL) in a thriller.
Ray Edwards blocks an [Eagles](/teams/philadelphiaeagles/profile?team=PHI) field goal attempt and Donald Strickland goes the other way for a wild turn of events for the [49ers](/teams/sanfrancisco49ers/profile?team=SF).
Juqua Parker picks off [49ers](/teams/sanfrancisco49ers/profile?team=SF) QB J.T. O'Sullivan and goes 55 yards for a game-sealing score as the [Eagles](/teams/philadelphiaeagles/profile?team=PHI) get a much-needed win.
The [Chargers](/teams/sandiegochargers/profile?team=SD) demonstrate their knack for excitement as [Philip Rivers](/player/philiprivers/2506121/profile) hits [Malcom Floyd](/player/malcomfloyd/2505785/profile) for a 49-yard scoring strike against the [Patriots](/teams/newenglandpatriots/profile?team=NE).