After an NFL-record 442 TD passes with the [Packers](/teams/greenbaypackers/profile?team=GB), Brett Favre hurls a 58-yard bomb to [Jerricho Cotchery](/player/jerrichocotchery/2506004/profile) for his first with the [Jets](/teams/newyorkjets/profile?team=NYJ).
With their kicker out of the game with an injury, [Jets](/teams/newyorkjets/profile?team=NYJ) fans get their first good glimpse of Favre's on-the-field magic on this fourth-and-12 play for a TD.
Rookie [Matt Ryan](/player/mattryan/310/profile) becomes the first quarterback since 2000 to throw for a touchdown on his first career pass attempt.
Michael Turner breaks through the [Lions](/teams/detroitlions/profile?team=DET) defense for a 66-yard TD run that highlighted a 220-yard [Falcons](/teams/atlantafalcons/profile?team=ATL) debut for the runner known as "the Burner."
Roy Williams does his best to keep his [Lions](/teams/detroitlions/profile?team=DET) in the game against the new-look [Falcons](/teams/atlantafalcons/profile?team=ATL) with this high-flying touchdown catch.
The [Ravens](/teams/baltimoreravens/profile?team=BAL) go to the old bag of tricks when Mark Clayton goes the distance on a double reverse, with a little help from rookie QB [Joe Flacco](/player/joeflacco/382/profile).
Seeing a 6-foot-6, 230-pound QB scrambling for a 38-yard TD is a surprise, but it wouldn't be if you saw [ his combine performance](/videos?categoryId=events&filter=combine&videoId=09000d5d806db0ef) six months ago.
Spectacular special teams play helped spark the [Bills](/teams/buffalobills/profile?team=BUF)' eye-opening rout of the [Seahawks](/teams/seattleseahawks/profile?team=SEA), starting with this rousing return by Roscoe Parrish.
Receiver [Nate Burleson](/player/nateburleson/2505511/profile) produced the [Seahawks](/teams/seattleseahawks/profile?team=SEA)' only memorable play in Sunday's humbling loss to the [Bills](/teams/buffalobills/profile?team=BUF), but then [left the game with an injury](http://blogs.nfl.com/2008/09/07/burleson-expects-to-play-next-week/).
It was simply Philly's day, as Donovan McNabb hit Hank Baskett for a 90-yard touchdown score in a lopsided 38-3 win over the [Rams](/teams/st.louisrams/profile?team=STL).
The [Panthers](/teams/carolinapanthers/profile?team=CAR) cap an exciting back-and-forth tussle in San Diego with a last-second touchdown from Jake Delhomme to Dante Rosario.