After an NFL-record 442 TD passes with the
[Packers](/teams/greenbaypackers/profile?team=GB), Brett Favre hurls a 58-yard bomb to
[Jerricho Cotchery](/player/jerrichocotchery/2506004/profile) for his first with the
[Jets](/teams/newyorkjets/profile?team=NYJ).
With their kicker out of the game with an injury,
[Jets](/teams/newyorkjets/profile?team=NYJ) fans get their first good glimpse of Favre's on-the-field magic on this fourth-and-12 play for a TD.
Rookie
[Matt Ryan](/player/mattryan/310/profile) becomes the first quarterback since 2000 to throw for a touchdown on his first career pass attempt.
Michael Turner breaks through the
[Lions](/teams/detroitlions/profile?team=DET) defense for a 66-yard TD run that highlighted a 220-yard
[Falcons](/teams/atlantafalcons/profile?team=ATL) debut for the runner known as "the Burner."
Roy Williams does his best to keep his
[Lions](/teams/detroitlions/profile?team=DET) in the game against the new-look
[Falcons](/teams/atlantafalcons/profile?team=ATL) with this high-flying touchdown catch.
The
[Ravens](/teams/baltimoreravens/profile?team=BAL) go to the old bag of tricks when Mark Clayton goes the distance on a double reverse, with a little help from rookie QB
[Joe Flacco](/player/joeflacco/382/profile).
Seeing a 6-foot-6, 230-pound QB scrambling for a 38-yard TD is a surprise, but it wouldn't be if you saw
[ his combine performance](/videos?categoryId=events&filter=combine&videoId=09000d5d806db0ef) six months ago.
Spectacular special teams play helped spark the
[Bills](/teams/buffalobills/profile?team=BUF)' eye-opening rout of the
[Seahawks](/teams/seattleseahawks/profile?team=SEA), starting with this rousing return by Roscoe Parrish.
Receiver
[Nate Burleson](/player/nateburleson/2505511/profile) produced the
[Seahawks](/teams/seattleseahawks/profile?team=SEA)' only memorable play in Sunday's humbling loss to the
[Bills](/teams/buffalobills/profile?team=BUF), but then
[left the game with an injury](http://blogs.nfl.com/2008/09/07/burleson-expects-to-play-next-week/).
Brian Moorman-to-Ryan Denney isn't exactly Jim Kelly-to- Andre Reed, but it contributed to the most points scored by the Bills in Week 1 since 1993.
Reggie Bush puts the Saints up for good with this 42-yard catch and run that ended with an acrobatic leap into the end zone.
It was simply Philly's day, as Donovan McNabb hit Hank Baskett for a 90-yard touchdown score in a lopsided 38-3 win over the
[Rams](/teams/st.louisrams/profile?team=STL).
The
[Panthers](/teams/carolinapanthers/profile?team=CAR) cap an exciting back-and-forth tussle in San Diego with a last-second touchdown from Jake Delhomme to Dante Rosario.
Matt Forte's first NFL touchdown comes on a 50-yard burst against the Colts en route to a 123-yard debut.
Charles Tillman strips the ball and Lance Briggs takes the fumble in for a touchdown against the Colts.