Taylor zipped a 13-yard touchdown pass over the middle to LeSean McCoy to cap his fourth and final series. Backup EJ Manuel then secured the win by leading two touchdown drives on an afternoon that began with Buffalo cutting backup running back Karlos Williams and announcing defensive tackle Marcell Dareus was entering a rehabilitation clinic.
The Bills gave up on Williams, who reported to training camp out of shape and was also suspended by the NFL for violating the league's substance abuse policy.
Dareus' decision to seek help came four days after Buffalo's top-paid player was suspended for violating the league's substance abuse policy for a second consecutive season.
Dareus was suspended for the first four games this season. General manager Doug Whaley didn't know when Dareus would check into a rehab facility or how long the process would take.
"I feel this is the best decision for me, my family and my teammates as I move forward with my career," Dareus said in a statement released by the team.
Manning completed 4 of 9 passes for 44 yards in four series, in which New York combined for 33 yards of offense and one first down. Beckham had one catch for 33 yards, and was targeted three times.
Nassib missed his first seven attempts before hitting rookie tight end Jerell Adams for an 8-yard completion to open his eighth series. Nassib finished 2 of 12 for 25 yards.
Copyright 2016 by The Associated Press