It was over when ...
Eagles WR DeSean Jackson continued to show why he is such a big-play threat, coming up with six catches for 140 yards and a touchdown. Jackson has 1,087 yards this season, becoming the third Eagles receiver under Andy Reid to reach 1,000. Jackson's 19-yard touchdown catch was his first score under 35 yards this season.
The 49ers doomed themselves from the get-go, committing four turnovers in the first half, including three interceptions thrown by Smith.
Philadelphia's 94-yard drive that ended with McNabb scoring on an 8-yard run was the Eagles' longest drive this season ... While the 49ers have been eliminated from playoff contention, the Cardinals have clinched the NFC West for the second straight year. ... 49ers RB Frank Gore rushed 16 times for 107 yards, snapping the Eagles' 23-game streak without allowing a 100-yard rusher. ... With three catches for 43 yards, Vernon Davis set a 49ers record for receiving yards for a tight end in a single season (858).