The NFL playoff picture is finally crystalizing -- or is it? If there is one truism to this 2021 season, it is this: The more we know, the less we know. With that, Jim Trotter takes one more look into his murky crystal ball.

Little has materalized on the "Larry Fitzgerald NFL return" front since the offseason. And the veteran free agent, whose spent his whole career with the Cardinals, intends to keep that way despite the injury to DeAndre Hopkins.

Cardinals running back Chase Edmonds is set for his return after being activated from injured reserve while WR DeAndre Hopkins was officially placed on IR.

Cardinals receiver DeAndre Hopkins will undergo surgery on his injured knee and will be out the rest of the regular season, according to Ian Rapoport. However, there is a chance he could be back for the playoffs.

Arizona could be without one of its key receivers for its Week 15 matchup against Detroit Lions.

The Rams won't have one of their best players when they take on the Cardinals on "Monday Night Football." The team announced Monday that cornerback Jalen Ramsey has been placed on the reserve/COVID-19 list.

Quarterback Kyler Murray and receiver DeAndre Hopkins will play against the Bears, Cardinals coach Kliff Kingsbury confirmed to NFL Network's Stacey Dales ahead of Sunday's clash.

Injury and roster news from Friday, including the Washington Football Team ruling out safety Landon Collins and running back J.D. McKissic. 

Michael F. Florio breaks down the top fantasy football matchups for Week 13 of the 2021 NFL season.

Kyler Murray has had a month to get his ankle right, which means he's had a lot of time to think about his injury. Both he and DeAndre Hopkins took the practice field on Wednesday. They just might return to game action together, too.

The Cardinals could welcome two of their top players back in time for a Week 13 contest against the Bears. Plus, other news from around the NFL on Wednesday.

The Cleveland Browns will be without offensive tackle Jack Conklin for the remainder of the 2021 season. NFL Network Insider Ian Rapoport reported Conklin suffered a torn patellar tendon during Sunday's loss to the Ravens.

Kyler Murray will once again be a game-time decision for the Arizona Cardinals. Coach Kliff Kingsbury said Friday that the Cards would take it down to the wire with the MVP candidate, noting that Murray has to be able to protect himself from re-injuring his ankle to play Sunday against the Seahawks.

Aiming to maintain the top spot in the NFC, the Cardinals will have to do so without their franchise quarterback and his No. 1 wide receiver for a second consecutive week.

Arizona Cardinals wide receiver DeAndre Hopkins, who didn't practice this week due to a hamstring injury, is unlikely to play against the Carolina Panthers on Sunday, according to NFL Network Insider Ian Rapoport. 

Kyler Murray and DeAndre Hopkins' statuses for Sunday's game against the Panthers will once again come down to the wire. Cardinals coach Kliff Kingsbury said Friday that Murray and Hopkins would once again be game-time decisions.

Michael F. Florio breaks down the top fantasy football matchups for Week 10 of the 2021 NFL season.

There's a new No. 1 in David Carr's top 15 offensive player rankings at the midway point of the 2021 NFL season. See how the pecking order shakes out heading into the second half.

After not logging a single practice this past week, Cardinals QB Kyler Murray and WR DeAndre Hopkins will not play against the 49ers in Week 9.

Arizona Cardinals quarterback Kyler Murray didn't practice this week because of an ankle injury and will try to go, but there isn't a lot of optimism, according to Ian Rapoport.

The Panthers hope to have their starting backfield healthy and ready to go in Week 9. Carolina coach Matt Rhule is "hopeful" that RB Christian McCaffrey (hamstring) will play Sunday against the Patriots.

David Carr says the New York Jets can help rookie quarterback Zach Wilson ... by sticking with Mike White. Plus, two other quarterback scenarios to track and an updated ranking of the top 15 offensive players in the NFL today.

Cardinals wideout DeAndre Hopkins left Thursday's game, was questionable to return, looked like he would be ruled out, but eventually came back in. In all, he played just 14 plays and had two catches for 66 yards in the Cardinals' 24-21 defeat. 

DeAndre Hopkins is active for the Arizona Cardinals' home game against the Green Bay Packers to open Week 8 on Thursday Night Football. 

Matthew Stafford and Cooper Kupp have made sweet music together this fall in Los Angeles, but according to Nick Shook, the Rams' prolific pairing isn't the very best pitch-and-catch combo in the NFL today. Check out the top 10.

Watch the 10 best highlight plays made by the Arizona Cardinals in the 2021 NFL season.

Watch Arizona Cardinals wide receiver DeAndre Hopkins' top plays during the NFL 2021 season.

Watch the Arizona Cardinals best plays from the month of December in the 2021 season.

The "Good Morning Football" crew discuss how Arizona Cardinals will rebound after losing wide receiver DeAndre Hopkins.

NFL Network's Ian Rapoport, Mike Garafolo reports Arizona Cardinals wide receiver DeAndre Hopkins expected to be placed on IR after knee surgery.

NFL Network's Ian Rapoport reports that Arizona Cardinals wide receiver DeAndre Hopkins status 'up in the air' vs. Detroit Lions.

Arizona Cardinals wide receiver DeAndre Hopkins makes a toe-tapping catch on the sideline on a pass from quarterback Kyler Murray on third down.

NFL Network's Kimmi Chex and Adam Rank give their 'Monday Night Football' projections for the NFC West showdown between the Los Angeles Rams and the Arizona Cardinals in Week 14 of the 2021 NFL regular season on 'NFL Fantasy Live' for wide receivers Cooper Kupp and DeAndre Hopkins, running back Sony Michel, and quarterback Kyler Murray.

NFL analyst Brian Baldinger breaks down the Arizona Cardinals win over the Chicago Bears in Week 13 of the 2021 season.

David Carr presents his favorite throws from Week 13 in his 'David's Dimes' segment on "NFL Total Access."

Arizona Cardinals quarterback Kyler Murray's first TD pass since Week 7 is pinpoint dime to wide receiver DeAndre Hopkins.

NFL Network's Ian Rapoport, Mike Garafolo report Wednesday's injury update for Arizona Cardinals quarterback Kyler Murray in Week 13.

Watch every Arizona Cardinals touchdown through 11 weeks of the 2021 season.

NFL Network Insider Ian Rapoport says it's "hard to imagine" Arizona Cardinals wide receiver DeAndre Hopkins plays vs. Seahawks Week 11.

Check out the head-to-head matchup that is expected to have the biggest impact in each game from Week 10

Watch the Arizona Cardinals best plays through the first 9 weeks of the 2021 season.

NFL Insider Ian Rapoport offers latest injury updates on Arizona Cardinals quarterback Kyler Murray and DeAndre Hopkins ahead of Week 10 vs. the Carolina Panthers.

Arizona Cardinals head coach Kliff Kinsbury details quarterback Kyler Murray and wide receiver DeAndre Hopkins return status for Week 10.

The top 5 longest throws by air distance through Sunday from Week 8 of the 2021 NFL season, according to Next Gen Stats.

Arizona Cardinals wide receiver DeAndre Hopkins makes 11-yard grab vs. Green Bay Packers cornerback Eric Stokes after returning from injury.

Can't-Miss Play: Arizona Cardinals quarterback Kyler Murray unloads a 55-yard sideline bomb to wide receiver DeAndre Hopkins.

NFL Network's Nick Shook's Top 10 QB-WR duo rankings for 2021 so far.

NFL Network Kurt Warner's must-watch quarterback-wide receiver duos in NFL right now.

Next Gen Stats might prove the Arizona Cardinals have the edge on the Green Bay Packers in Week 8. Catch all the action starting Thursday at 8:20 PM ET on NFL Network.

NFL analyst Brian Baldinger breaks down the offensive and defensive strengths of the Arizona Cardinals from their Week 7 win over the Houston Texans.