Jeremiah: Key matchups in Week 8
Daniel Jeremiah identifies five enticing battles to follow in Week 8, including DeSean Jackson vs. Asante Samuel. More ...
"It's a challenge for everybody," Harbaugh said, via the San Francisco Chronicle. "In this league, call it a struggle, call it a challenge. Every single week, that's a challenge and an opportunity for both teams."
Some teams are more "challenged" than others. ESPN analyst Jon Gruden wasn't as kind with his evaluation.