District Attorney Seth Williams said Monday there was insufficient evidence to warrant any charges.
Police had received an allegation that Agholor was involved in a sex assault June 9 at the Cheerleader's Gentlemen's Club.
The district attorney said a joint investigation was conducted by his office's sex assault unit and the police department's Special Victims Unit.
The 23-year-old Agholor played at Southern California and was a 2015 first-round draft pick for the Eagles. His lawyer has said Agholor was not involved in any criminal conduct whatsoever.
Copyright 2016 by The Associated Press