He died Friday at his home in Eastlake, Ohio, outside Cleveland, the Giants said in a statement Saturday. No cause was given.
Modzelewski spent 14 years in the NFL, eight with the Giants that included six title games. He teamed with Andy Robustelli, Rosey Grier and Jim Katcavage on one of the great defensive lines.
Modzelewski also appeared in two championship games with the Browns. He joined the NFL with Washington in 1953 and also played for Pittsburgh, never missing a game in his career.
Modzelewski was an All-American in 1951 and '52 at Maryland and won the Outland Trophy in 1952 as the nation's best lineman. It resulted in an invitation to the White House, where he had lunch with President Dwight Eisenhower. He was inducted into the College Football Hall of Fame in 1993.
Modzelewski was traded to the Browns in 1964 for wide receiver Bobby Crespino. He was expected to be a backup but became a starter when Frank Parker was injured. Cleveland played in the championship game in each of Modzelewski's first two seasons, beating Baltimore in 1964 and then losing to Green Bay.
Modzelewski is survived by his wife of 64 years, Dorothy Jane, and four children.
A funeral is set for Oct. 26 in Mentor, Ohio.