McCoy -- who finished 3-of-7 passing for 41 yards with the pick -- was replaced in the lineup by Scott Tolzien. McCoy played the 49ers' second, third and seventh series of the first half. Tolzien played the fourth, fifth, sixth and eighth series. Tolzien also started the second half. The two quarterbacks have been splitting second-team reps in practice.
"There's nothing shown there. It's very even," Harbaugh said, via CSN Bay Area. "And (I'm) very much looking forward to the games and future practices to determine (it). It's not clear-cut at that position."
Injury troubles are nothing new for McCoy. But the timing of his latest malady could have serious consequences.