Matthews hit Colin Kaepernick well after the 49ers quarterback went out of bounds during a third-down play in the second quarter, setting off a prolonged skirmish between both teams. Matthews was penalized on the play for a personal foul, but 49ers offensive tackle Joe Staley had an offsetting unsportsmanlike-conduct penalty.
The play proved to be a big turning point in San Francisco's 34-28 home victory. The two dead-ball fouls should have been offsetting penalties and a loss of down, but Fox's Mike Pereira pointed out that the officials made a mistake and played the down again. The 49ers wound up scoring a touchdown with the extra down.