Starting strong safety Horton damaged a ligament in his left big toe in Sunday's 31-17 loss to Atlanta. He's out a minimum of four to six weeks -- and it'll be four to six months if a specialist decides the toe needs surgery.
Offensive lineman Williams, who has started the last four games, is out two to four weeks with a ligament tear in his ankle.
Coach Jim Zorn says the team will play it safe with Portis, who took a helmet-to-helmet blow during the first quarter on Sunday. Portis will undergo a test Tuesday to determine if he can play next week against Denver.
Copyright 2009 by The Associated Press