"Just got a bit of a little tweak," Caldwell said Saturday morning. "He won't play in the game obviously, but he'll be back soon."
Clark immediately received medical attention at practice Friday and left on a cart with a wrap around his upper left leg.
Clark tied wide receiver Reggie Wayne for the team lead in receptions (100) and touchdown catches (10) last season. Clark's 1,106 receiving yards were second-most on the team.