Massaquoi and Watson were both injured in the closing minutes of the first half.
Early during the third quarter, the team reported the injury to Watson. It's unclear when Watson was injured, but it's not believed he came out for the second half.
Last season, Massaquoi missed one game with a concussion after he was hit by Pittsburgh linebacker James Harrison, who was fined for the helmet-to-helmet blow.
The Associated Press contributed to this report