Gonzalez will be on the field for the first time since Week 1. The receiver had been sidelined with an ankle problem.
As expected, running back Joseph Addai and wide receiver Austin Collie are inactive and will not play.
Addai injured his shoulder in Week 6 and there is no timetable for his return. Collie had surgery on his right thumb during Indianapolis' bye week and is out indefinitely.
The Associated Press contributed to this report.