- Atlanta Falcons safety Richie Grant suffered an ankle injury against the Buccaneers and did not return. Linebacker Adetokunbo Ogundeji also suffered an ankle injury.
- Baltimore Ravens offensive tackle Patrick Mekari injured his hand against the Steelers. John Harbaugh said after the game that cornerback Marlon Humphrey is set to undergo an MRI for an unspecified injury, adding that it "could be a while" before he returns to the lineup. NFL Network Insider Ian Rapoport reported Humphrey is suspected to have suffered a season-ending shoulder injury.
- Cincinnati Bengals linebackers Markus Bailey (shoulder) and Logan Wilson (shoulder) were ruled out against the Chargers. Cornerback Chidobe Awuzie suffered a foot injury.
- The Houston Texans announced quarterback Tyrod Taylor was evaluated for injury and cleared to play but was replaced by rookie Davis Mills against the Colts.
- Jacksonville Jaguars offensive lineman Brandon Linder (back) and cornerback Tyson Campbell (abdominal) exited early against the Rams.
- Las Vegas Raiders running back Kenyan Drake suffered a broken ankle on Sunday is out for the season, Rapoport reported. In his first season with Las Vegas, Drake was the team's second-leading rusher. Linebacker Nick Kwiatkoski (ankle) was also ruled out. Linebacker Denzel Perryman (ankle) exited early.
- Los Angeles Chargers defensive end Joey Bosa was ruled out after exiting in the first half against the Bengals to be evaluated for a head injury.
- Miami Dolphins running back Patrick Laird suffered a knee injury against the Giants and was ruled out.
- Minnesota Vikings wideout Adam Thielen was ruled out against the Lions with an ankle injury that NFL Network's Tom Pelissero reports is a high ankle sprain. Pelissero added Thielen will undergo further testing to determine the severity.
- The New England Patriots announced linebacker Ronnie Perkins (illness) has been downgraded to out for Monday's game against the Bills.
- New York Giants quarterback Mike Glennon sustained a concussion against the Dolphins. Glennon started in place of Daniel Jones, who did not play due to a neck injury.
- New York Jets cornerback Michael Carter was evaluated for a concussion. Guard Laurent Duvernay-Tardif (ankle) did not return against the Eagles. Tight end Ryan Griffin (ankle) and wideout Corey Davis (ankle) also did not return.
- Philadelphia Eagles linebacker Patrick Johnson (back) and cornerback Steven Nelson (shoulder) were ruled out against the Jets. Running back Miles Sanders (ankle) was also ruled out.
- San Francisco 49ers running back Trenton Cannon was taken off the field in an ambulance after sustaining a concussion on the opening kickoff against the Seahawks. Cannon was transported to a local hospital for further evaluation, per the game's broadcast. The Niners announced he is in stable condition and will stay at the hospital overnight. Cornerback Emmanuel Moseley (ankle) has also been ruled out. Safety Jaquiski Tartt injured his hamstring. Running back Elijah Mitchell was evaluated for a head injury.
- Seattle Seahawks guard Kyle Fuller suffered an ankle injury against the 49ers. Safety Jamal Adams (shoulder) was ruled out. Defensive tackle Bryan Mone (knee) did not return.
- Tampa Bay Buccaneers cornerback Jamel Dean was ruled out against the Falcons after being evaluated for a concussion. Running back Ronald Jones (illness) did not return.
- Washington Football Team tight end Logan Thomas is expected to be done for the season after likely sustaining a torn ACL, Rapoport reported. Thomas will have an MRI to confirm. Thomas was injured when Raiders defensive end Yannick Ngakoue dropped down to avoid a Thomas block and took out the tight end's leg. Linebacker Khaleke Hudson (ankle) exited early versus the Raiders.
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Falcons name Ryan Nielsen as new defensive coordinator
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Dolphins QB Tua Tagovailoa remains in concussion protocol, won't participate in Pro Bowl Games
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Chiefs QB Patrick Mahomes to start in AFC title game vs. Bengals despite high ankle sprain
As expected, Patrick Mahomes will start Sunday's AFC Championship Game against the Bengals despite a high ankle sprain. "He looks good," Chiefs coach Andy Reid said Friday of Mahomes. "He's moving around good."
49ers DC DeMeco Ryans emerging as top candidate for Texans' head coaching job
DeMeco Ryans is spending the week preparing for his team's biggest game to date. He might soon be packing his belongings for a new club entirely. The 49ers DC has emerged as a top candidate for the Texans' head coaching job.
NFL news roundup: Latest league updates from Friday, Jan. 27
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Rams hire former Jets OC Mike LaFleur as new offensive coordinator
The moment Mike LaFleur parted ways with the New York Jets, the Los Angeles Rams became the favorite to land the former offensive coordinator. The ship landed on Friday.
Steve Wilks 'disappointed but not defeated' after not getting Panthers' head coaching job
Steve Wilks is taking the high road after being passed over for the Panthers head coaching job. The day after Carolina announced it hired Frank Reich as its next coach, Wilks sent a message on social media thanking his former players and coaches.
Sauce Gardner 'wouldn't mind' if Aaron Rodgers joined Jets: 'I just want what's best for the offense'
Aaron Rodgers continues to debate his future, whether it be retirement, returning to Green Bay or changing cities. After Nathaniel Hackett's hire in New York, every Jets player, including Sauce Gardner, is being asked about a possible Rodgers addition.
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