Only three of Sunday's matchups pit teams with winning records against each other. (Extra points if in the preseason you knew the New York Jets versus the Tennessee Titans would be one of those games.) These are the things you need to know for all of Sunday's games as kickoff approaches.
Key game-time decisions
Pryor threw at practice Friday, made "significant process" in his recovery and was medically cleared to play. The signs are there for QB1 to play, but the Raiders waited to be certain he's not feeling the aftereffects of the concussion he suffered in Week 3. Although Pryor has been cleared to play Sunday, Matt Flynn is preparing to start as he has been all week, NFL Media Insider Ian Rapoport reported.
Both receivers returned to practice Friday as limited participants. We expect both to play. Rookie Mike Glennon needs all the help he can get in his first career start.
The weekly "Falcons wide receivers are questionable" routine continues. As with last week, we expect both to play.
Matching up against DeSean Jackson and the Philadelphia Eagles' offense, the Broncos hope both will be healthy enough to see the field. Bailey hasn't played yet this season, while Ihenacho has keyed the back end of the 3-0 Broncos' defense.
Davis was limited all week after missing last week's game. Reed has been a pleasant surprise thus far this season. While he returned to practice Friday, reports out of Washington didn't sound optimistic about his availability Sunday in Oakland.
Key quarterbacks who need to step up
After watching Sam Bradford bomb on "Thursday Night Football," let's look at some other non-rookie quarterbacks playing Sunday to keep an eye on.
Dear Andy: You have the weapons. Please, stop wasting them. You don't want to be compared to Bradford and Josh Freeman for the next week.
Schaub has struggled mightily to start the season. He has to avoid the killer interception against the NFL's best defense.
It is probably the last stand for Gabbert. He'll be given every chance to prove he can be the quarterback of the future. I'm not optimistic he will.
Stafford has improved this season, but he hasn't been the difference-maker the Lions' offense needs. With a lack of reliable receivers, the Lions need him to be a playmaker against the Chicago Bears (against whom he is 1-5 in his career). More than anything, Stafford can't give an opportunistic defense the chance to score.
My Magic Eight Ball tells me we'll be talking about RGIII's knee brace again Monday, win or lose.
Locker has made plays with his feet and has been a leader thus far in 2013. He still doesn't throw the most accurate ball, but if he can lead the Titans' offense to a win against the Jets' defense, it would speak volumes about his future.
Which Cassel will we get? The one who led a consistent offense in Kansas City en route to a 2010 Pro Bowl selection, or the turnover-prone one we saw the past couple of seasons? It's his chance to pilfer another starting gig if he lights up the Pittsburgh Steelers' defense.
Did you know?
» How crazy has the season been through three weeks?
There have been eight games this season in which a team was trailing and scored the game-winning points in the final minute of the fourth quarter, the most through the first three weeks of a season since at least the 1970 merger.
» Five of the six games played in London since 2007 have featured a 100-yard running back. Brandon Jacobs (131 yards), LaDainian Tomlinson (105), Frank Gore (118), Matt Forte (145) and Stevan Ridley (127) all have cracked the century mark at Wembley Stadium. That is a good stat for Adrian Peterson.
There isn't a scenario I legitimately can come up with in which Joe Flacco does not pick apart what is left of the carcass that is the Buffalo secondary.
The loss of Henry Melton quite possibly could be the biggest injury almost no one is talking about. If the Bears let Matthew Stafford stand in the pocket all afternoon, Calvin Johnson will have a big day.
Just turn the crank, and snap the plank, and boot the marble right down the chute. Now watch it roll, and hit the pole, and knock the ball in the rub-a-dub-tub, which flips the man right into the pan. The trap is set. Here comes the net. Mouse Trap! I guarantee, it's the craziest trap you'll ever see!
The Jags disputed reports that they had to resort to ball boys, equipment assistants and practice squad quarterback Matt Scott as wide receivers on the scout team during practice this week. So there is that.
Chiefs QB Alex Smith just doesn't turn the ball over. That really is one of the only things keeping him from being lumped in with other struggling quarterbacks. I guess 7-yard spikes are better than a 30-yard interceptions. (Assuming you have the defense to bail you out of every situation.)
Rookie Mike Glennon starting this week heading into a bye week makes sense so that Bucs coach Greg Schanio can get some game tape on him to study. It also helps going against a Cardinals defense missing a bevy of defensive starters.
The Jets are looking at a near mirror image of themselves again this week. The trouble has been that they run directly into that mirror like an excited 2-year-old and get called for a personal foul penalty.
How good has the Titans' defense been? No one is talking about Alterraun Verner, who is allowing a measly 23.3 QB rating when thrown at, according to Pro Football Focus. That nearly is seven points lower than second place, Richard Sherman's 30.1. Some advice for Geno Smith: just look to the other side of the field.
This game has to be 76-70 for the Eagles to have a shot, right? Peyton Manning has picked apart much better defenses. I could see him decide to protect his defense against Chip Kelly's offense by leading multiple double-digit touchdown drives. Not because he has to. No, because he can.
Kelly's offense won't see the same caliber defense it did last week, but this could be the toughest test he's faced so far in determining whether his quick-strike offense can sustain consistency versus a precision, high scoring machine in Manning.
This could be a bad game to be a defense. Yes, RGIII coming off an ACL injury isn't Peyton Manning, but the Raiders can't have the defensive breakdowns and miscommunications in the secondary they displayed last week. Even Peter Griffin could exploit those problems.
The San Diego Chargers could (read: should) be 3-0. I'm just going to let that marinate.
The Patriots' defensive backs were picked on by big receivers last week against the Buccaneers. They get the souped-up version this week. Julio Jones in particular should see plenty of chances to exploit the Pats' secondary.
Tom Brady didn't stretch the field much last week. Instead he just bled the defense with paper cuts until they wilted. Until he gets in tune with his rookie receivers, I expect he'll employ that strategy again.