The 16th matchup between the all-time great quarterbacks wasn't particularly competitive after the first quarter.
New England (7-2) won its fifth straight, halting the four-game winning streak for Denver (6-2) in emphatic fashion. Brady has 18 TD passes and one interception in those five victories.
Manning fell to 2-7 at Gillette Stadium and 5-11 overall against Brady, even though he threw for 438 yards and two touchdowns. He has at least two TD passes in 14 consecutive games, an NFL record.
In his 200th career start, Brady passed for 333 yards. He has won 155 of those, the most for any quarterback in that many starts.
Copyright 2014 by The Associated Press