The linebacker was placed on the physically unable to perform list, the team announced Tuesday. Houston will miss at least the first six games of the season.
The 27-year-old pass rusher battled knee issues in 2015, missing five games. He didn't look right when he returned for the Chiefs' two playoff contests.
During the summer, Houston scoffed at the notion he would miss the entire season and the Chiefs have insisted all offseason that Houston will return at some point. He will, however, miss at least six games. Getting the pocket wrecker back by midseason could give K.C. a boost towards another playoff run.