On Thursday, those struggles came to a head versus a swelling Seattle defense.
Harbaugh admitted his team probably has to win its remaining four games to make the playoffs. The coach was asked if it was time to evaluate his offense and make major changes in order to make a run.
"We always do that," he said, per the San Jose Mercury News. "We'll do that again. We'll evaluate it. I don't know what you refer to with major changes."
Offensive coordinator Greg Roman sits in the eye of the fans' dismay, with some in San Francisco clamoring for his firing.
However, the two situations aren't exactly analogous. With the 49ers' season already in peril and Harbaugh seeming destined to leave at the year's end, an in-season shakeup seems unlikely. A move would not magically solve the issues, and, as the Mercury News' Tim Kawakami notes, making drastic maneuvers has never been Jim Harbaugh's style.