Sanders played just 24 snaps in Sunday's win over Tennessee before exiting with a knee injury.
The 32-year-old receiver practiced on Tuesday, a good indication he would be back on the field this week. Sanders has 307 receiving yards on 25 catches with two TDs, including a 104-yard performance in Week 4. The last two games, however, he has just nine yards on two receptions while dealing with injury.
On the Chiefs' side, K.C. continues to deal with a plethora of injuries. Receiver Sammy Watkins (hamstring), LT Eric Fisher (groin), CB Kendall Fuller (thumb), DT Chris Jones (groin) and LG Andrew Wylie (ankle) have all been ruled out. Corner Bashaud Breeland (not injury related) is questionable to play.