Losing Clady is a big blow for the Broncos. But he has not been the same since a foot injury in 2013, and the Broncos are installing a new system under Kubiak. The timing of the injury allows Kubiak to prepare multiple options for the left tackle job, and Peyton Manning's quick release helps out any offensive linemen.
It's a season of transition in Denver, even as their Super Bowl window remains open. The loss of Clady just speeds up the change on the offensive line, where the team could have new four starters.