It's the first missed game for Megatron since the 2010 season finale. He routinely plays despite missing practice time, so there was optimism throughout this week that he would be able to suit up against the Green Bay Packers.
Detroit's receiver group already was thin heading into this game. Nate Burleson is out after his pizza-infused car accident. Ryan Broyles doesn't seem all the way back from his ACL tear, even though he's on the field. The team will ask Reggie Bush, receiver Kris Durham and its tight ends to carry the load more than usual.