Mahomes talks about how underwear is his secret weapon

Watch the best of Monday Night Football with Peyton & Eli during Super Wild Card Weekend of the 2023 NFL season.

Former linebacker Ray Lewis and Manning bros react to Tampa Bay Bucs' safety.

Former linebacker Ray Lewis describes the complications of changing defensive coordinators midseason.

Former Tampa Bay Buccaneers head coach Bruce Arians reveals he is the origin of the 'Omaha' audible.

Bruce Arians and Manning bros react to Philadelphia Eagles' failed 'tush-push' vs. Tampa Bay Bucs.

Former Tampa Bay Buccaneers head coach Bruce Arians explains his 'no risk it, no biscuit' philosophy.

Former Tampa Bay Buccaneers head coach Bruce Arians praises Baker Mayfield's charisma as quarterback for the Bucs.

Former Tampa Bay Buccaneers head coach Bruce Arians reveals what it was like coaching Peyton Manning as a rookie.

Peyton and Eli Manning react to Tampa Bay Bucs' electric 44-yard touchdown connection.

Eli Manning demonstrates how the middle finger affects throwing the football.

Watch the best of Monday Night Football with Peyton & Eli in Week 15 of the 2023 NFL season between the Seattle Seahawks and Philadelphia Eagles.

The Manning brothers react to the clutch fourth quarter Seattle Seahawks drive during Week 15 of the 2023 NFL season on the ManningCast.

Analyst and reporter Mina Kimes talks about her etch-a-sketch football drawings during the ManningCast in Week 15 of the 2023 NFL season.

Analyst and reporter Mina Kimes shares why she believed in Philadelphia Eagles quarterback Jalen Hurts before he was the starter in Philadelphia during the ManningCast in Week 15 of the 2023 NFL season.

Analyst and reporter Mina Kimes talks about her Seattle Seahawks fandom during the ManningCast in Week 15 of the 2023 NFL season.

Eli Manning talks about his influence on Seattle Seahawks wide receiver DK Metcalf and Philadelphia Eagles wide receiver A.J. Brown during the ManningCast in Week 15 of the 2023 NFL season.

ESPN's Mina Kimes comments on the variety of facial expressions of Philadelphia Eagles head coach Nick Sirianni.

Mina Kimes reflects on her reaction to wide receiver DK Metcalf getting drafted by the Seattle Seahawks.

Peyton and Eli Manning react to Seattle Seahawks' third-quarter touchdown.

Houston Texans quarterback Case Keenum talks possibility of playing vs. his former team.

Houston Texans quarterback Case Keenum talks about how he felt during the Minnesota Miracle on the ManningCast in Week 15 of the 2023 NFL season.

Houston Texans quarterback Case Keenum shares how he tried to help Buffalo Bills quarterback Josh Allen during the ManningCast in Week 15 of the 2023 NFL season.

Houston Texans quarterback Case Keenum talks about the experience of playing backup QB.

Houston Texans quarterback Case Keenum answers questions about the Texans win over the Tennessee Titans as he fills in for comedian Kevin Hart during the ManningCast in Week 15 of the 2023 NFL season.

San Francisco 49ers running back Christian McCaffrey shares memories about playing against mascots and about learning football from his father during the ManningCast in Week 15 of the 2023 NFL season.