Colt McCoy audibles for big third-down throw to Darius Slayton

Watch all of San Francisco 49ers running back Christian McCaffrey's best plays from his 119-yard game on 'Thursday Night Football' against the New York Giants in Week 3 of ther 2023 NFL regular season.

Watch all of the highlights from the NFC showdown between the visiting New York Giants and the San Francisco 49ers on 'Thursday Night Football' in Week 3 of the 2023 NFL regular season.

Watch all of San Francisco 49ers wide receiver Deebo Samuel's best catches from his 129-yard game against the New York Giants on 'Thursday Night Football' on Week 3 of the 2023 NFL regular season.

San Francisco 49ers safety Talanoa Hufanga nabs a tip-drill interception late in the fourth quarter on a pass thrown by New York Giants quarterback Daniel Jones on 'Thursday Night Football' in Week 3 of the 2023 NFL regular season.

Watch the Next Gen Stats breakdown of San Francisco 49ers wide receiver Deebo Samuel's effort for 16 yards after the catch and the team's

San Francisco 49ers quarterback Brock Purdy launches back-shoulder touchdown dart to 49ers wide receiver Deebo Samuel despite intense pressure.

San Francisco 49ers tight end George Kittle's trademark stiff arm creates a 29-yard catch and run along the sideline.

New York Giants cornerback Darnay Holmes sniffs out the San Francisco 49ers' screen pass for a backfield tackle for a loss.

San Francisco 49ers wide receiver Deebo Samuel breaks FOUR tackles on a 40-yard run after the catch.

Track San Francisco 49ers wide receiver Deebo Samuel's 40-yard gain against the New York Giants on "Thursday Night Football."

New York Giants cornerback Darnay Holmes shows zero quit on a third-down pass break-up along the sideline.

New York Giants running back Matt Breida gets revenge TD against the San Francisco 49ers with an 8-yard scamper up the middle.

New York Giants wide receiver Darius Slayton hauls in a 17-yard loft from Giants quarterback Daniel Jones along the sidelines.

San Francisco 49ers rookie wide receiver Ronnie Bell locates the football off a WILD bounce for a 15-yard gain.

San Francisco 49ers running back Elijah Mitchell makes multiple New York Giants tacklers miss on an 18-yard burst.

San Francisco 49ers running back Christian McCaffrey powers through the middle for Niners' second touchdown of the night.

San Francisco 49ers defensive tackle Javon Hargrave gobbles up New York Giants quarterback Daniel Jones for his second sack as a member of the 49ers.

San Francisco 49ers rookie wide receiver Ronnie Bell's first NFL touchdown catch comes via 49ers quarterback Brock Purdy's backpedaling pass.

San Francisco 49ers wide receiver Deebo Samuel takes a tunnel screen for a 30-yard gain on third down.

San Francisco 49ers quarterback Christian M takes screen pass 16 yards to move the chains in the red zone.

New York Giants defensive lineman D.J. Davidson bats down San Francisco 49ers quarterback Brock Purdy's throw at the line of scrimmage.

New York Giants kicker Graham Gano's 44-yard field goal evens the 'Thursday Night Football' score in the first quarter of the team's road game against the San Francisco 49ers in Week 3 of the 2023 NFL regular season.

San Francisco 49ers quarterback Brock Purdy perfectly places a 15-yard pass to 49ers tight end George Kittle over a New York Giants defensive back's outstretched arms.

San Francisco 49ers rookie kicker Jake Moody puts the 49ers on the board first with a 28-yard field goal in their game against the New York Giants on 'Thursday Night Football' in Week 3 of the 2023 NFL regular season.

San Francisco 49ers defensive end Nick Bosa goes untouched for one of 2023's fastest sacks vs. New York Giants quarterback Daniel Jones.