Details: Saturday, 3:30 p.m. ET, CBS
What's at stake? Alabama can clinch the SEC West and get a step closer to the College Football Playoff, while Auburn looks to play the spoiler role at home. In the Iron Bowl, the underdog often puts up quite a fight, as Auburn did at home in 2009, and as Alabama did in 2010.
Matchup to watch: Alabama OL Cam Robinson vs. Auburn DE Carl Lawson.

Game picks:
Brandt: Alabama, 35-14
Brooks: Alabama, 28-20
Davis: Alabama, 49-10
Goodbread: Alabama, 41-13
Jeremiah: Alabama, 34-10
Reuter: Alabama, 28-17
Zierlein: Alabama, 35-14

Details: Saturday, 7:15 p.m. ET, ESPN2
What's at stake? The annual Egg Bowl brings with it bragging rights all across the Magnolia State. Beyond that, the Rebels maintain slim SEC title hopes reliant upon a win here, plus an upset of Auburn over Alabama.
Matchup to watch: Ole Miss DL Robert Nkemdiche vs. Mississippi State QB Dak Prescott.

Game picks:
Brandt: Mississippi State, 34-31
Brooks: Mississippi State, 21-20
Davis: Ole Miss, 36-26
Goodbread: Ole Miss, 31-24
Jeremiah: Ole Miss, 24-21
Reuter: Ole Miss, 24-20
Zierlein: Mississippi State, 34-28

Details: Houston earns berth in AAC title game with win over Navy | Houston WR makes stunning one-handed catch
What's at stake? The AAC West division is on the line here as two of the best Group of Five teams in the country vie for a potential spot in a New Year's Six bowl. If you've never seen Keenan Reynolds operate Navy's triple-option offense, treat yourself before the senior is gone.
Matchup to watch: Houston LB Efrem Oliphant vs. Navy QB Keenan Reynolds.

Game picks:
Brandt: Houston, 30-27
Brooks: Navy, 30-24
Davis: Houston, 28-27
Goodbread: Houston, 27-21
Jeremiah: Houston, 21-20
Reuter: Navy, 38-17
Zierlein: Navy, 31-28

Details: Saturday, 3:30 p.m. ET, ABC/ESPN2
What's at stake? Winner takes the Pac-12 South and a shot at the league title. This series dates back to 1929 and the rivalry can be fiery at times.
Matchup to watch: USC LB Su'a Cravens vs. UCLA RB Paul Perkins.

Game picks:
Brandt: USC, 30-27
Brooks: USC, 23-21
Davis: UCLA, 38-35
Goodbread: USC, 35-24
Jeremiah: UCLA, 31-28
Reuter: USC, 41-38
Zierlein: USC, 30-28

Details: Saturday, 3:30 p.m. ET, ESPN
What's at stake? A week after setting itself up for a possible College Football Playoff berth, the Spartans must guard against a letdown against Penn State. The Nittany Lions would put a much more positive spin on their season with a road upset here.
Matchup to watch: Michigan State DE Shilique Calhoun vs. Penn State QB Christian Hackenberg.

Game picks:
Brandt: Michigan State, 24-14
Brooks: Michigan State, 17-13
Davis: Michigan State, 27-20
Goodbread: Michigan State, 28-14
Jeremiah: Michigan State, 28-14
Reuter: Michigan State, 35-14
Zierlein: Michigan State, 24-13

Details: Saturday, 7:30 p.m. ET, ESPN
What's at stake? FSU will be playing for state pride in a rivalry game that has been known to foster its share of ill will. This is always among the most physical games of rivalry week. UF has a bit more to play for, as the Gators are two very difficult wins away from a possible playoff berth (FSU and, likely, Alabama in the SEC title game).
Matchup to watch: FSU OL Roderick Johnson vs. Florida DE Jon Bullard.

Game picks:
Brandt: Florida State, 21-17
Brooks: Florida State, 24-20
Davis: Florida State, 13-10
Goodbread: Florida State, 24-16
Jeremiah: Florida State, 24-17
Reuter: Florida, 27-21
Zierlein: Florida, 20-17

Details: TCU ends Baylor's playoff hopes in double overtime
What's at stake? Remember when the season began and conventional wisdom tabbed this as the game of the year in the Big 12? With three losses between them now, it's not that any longer. But Baylor's chances of winning a Big 12 title are riding on this game, even if a one-loss Bears team could be shut out of the playoff again.
Matchup to watch: Baylor CB Xavien Howard vs. TCU WR Kolby Listenbee.

Game picks:
Brandt: Baylor, 42-38
Brooks: Baylor, 43-40
Davis: Baylor, 45-40
Goodbread: Baylor, 47-31
Jeremiah: Baylor, 35-31
Reuter: Baylor, 53-45
Zierlein: Baylor, 45-35

Details: Saturday, Noon ET, ABC
What's at stake? The Big Ten's most classic rivalry has plenty of spice this year, even with Ohio State likely bowing out of the playoff hunt with its loss to Michigan State. There is Jim Harbaugh's debut as a coach in the series to add intrigue, not to mention whether OSU's offense can get off the mat against a stingy defense.
Matchup to watch: Ohio State WR Braxton Miller vs. Michigan DB Jabrill Peppers.

Game picks:
Brandt: Ohio State, 20-17
Brooks: Ohio State, 14-10
Davis: Ohio State, 21-17
Goodbread: Ohio State, 21-17
Jeremiah: Michigan, 21-20
Reuter: Ohio State, 28-27
Zierlein: Ohio State, 27-24

Details: Saturday, 8 p.m. ET, ABC
What's at stake? The Sooners have climbed back into the playoff race with back-to-back wins over Baylor and TCU. Another win here would give the Sooners an impressive case for the CFP selection committee. Meanwhile, the Cowboys look to rebound from a loss to Baylor.
Matchup to watch: Oklahoma LB Eric Striker vs. Oklahoma State QB Mason Rudolph.

Game picks:
Brandt: Oklahoma, 40-31
Brooks: Oklahoma, 24-21
Davis: Oklahoma, 35-31
Goodbread: Oklahoma, 41-35
Jeremiah: Oklahoma, 41-31
Reuter: Oklahoma, 45-42
Zierlein: Oklahoma, 38-35

Details: Saturday, 7:30 p.m. ET, FOX
What's at stake? The Cardinal can spoil Notre Dame's hopes for a playoff berth here. A couple of weeks ago, this game looked like it might be a CFP play-in game, but Stanford has since lost to Oregon and fallen out of the hunt. Given that the Fighting Irish have no conference title game to compete in, this is the team's last chance to make a big impression on the selection committee.
Matchup to watch: Notre Dame LB Jaylon Smith vs. Stanford G Joshua Garnett.

Game picks:
Brandt: Stanford, 35-28
Brooks: Notre Dame, 23-20
Davis: Stanford, 34-30
Goodbread: Notre Dame, 30-20
Jeremiah: Notre Dame, 24-21
Reuter: Stanford, 35-31
Zierlein: Stanford, 23-21