When Brock Osweiler takes the field for his first start Sunday, he will have waited 57 games for the opportunity. That's the fourth-longest wait of any player drafted in the first two rounds since 1950 (1960: Rudy Bukich 86; 1967: Billy Kilmer 84; and 1981: Glenn Carano 75).

Aaron Rodgers and Adrian Peterson have combined for three of the last four MVP awards (Rodgers 2, Peterson 1). They are the only two players not named Tom Brady or Peyton Manning to win an MVP since 2007.

Marcus Mariota has been lights out on the road this season, throwing 10 TDs and no INTs in his three road starts. Mariota's 133.8 passer rating on the road leads the NFL by a wide margin (Tyrod Taylor is second at 110.8).

Chris Johnson is second in the NFL in rushing yards this season (734) at age 30, while fellow 30-year-old Adrian Peterson leads the league with 961 rushing yards. Since at least 1932, there have never been two players age 30 or older to finish the season as the top two rushers.

Tom Brady is leading the NFL in passing yards per game (338.1), TD-INT ratio (8.00), and passer rating (111.1) this season. The last QB to lead the league in all three categories for a full season? Brady himself during his 2007 MVP season. Only three other QBs have accomplished the feat since 1950: Joe Montana in 1989 for the 49ers, John Brodie in 1970 for the 49ers, and Johnny Unitas for the Colts in 1957.

Cam Newton is one game behind Steve Young (31) for the most games in NFL history with a passing and rushing TD. In each of his two career games against the Redskins, Newton has picked up the win while throwing for and running in a TD. Will he tie Young's record Sunday?

Tony Romo returns to the lineup for the Cowboys this week after Dallas lost all seven games without him. Romo loves the month of November, in which he has a 26-6 (.813) career record. That's the third-highest mark for any QB since 1950, and the best since Daryle Lamonica (19-4-2), who last started a game in 1973.

DeAndre Hopkins has been targeted a league-high 123 times this season. Hopkins is on pace to pass Rob Moore (1997) for the most targets in a season since 1991 (208).

The Seahawks have lost back-to-back home games for the first time since 2011. Seattle hasn't lost three straight home games since dropping five in a row in 2008. Russell Wilson is 2-2 at home this year for Seattle. From 2012-2014, he was 22-2 at home.

Amari Cooper is on pace to nearly double Calvin Johnson's rookie output in 2007. In 15 games that season, Johnson caught 48 passes for 756 yards and four TDs. Cooper is currently on pace to finish his rookie season with 89 receptions, 1,301 yards, and seven TDs.