Winfield has been hampered by a hamstring injury that first flared up against Philadelphia last week and was tweaked during practice this week. Winfield did not practice on Thursday or Friday.
Winfield was bothered late in the year by a quad injury last season, but he played through that pain and is considered one of the toughest players on the team.
Winfield said this is the first time in his career that he has had a hamstring injury and expected that he would be a "gametime decision."
The Associated Press contributed to this report.